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经皮肾镜取石术——总是有效且无并发症吗?

[Percutaneous nephrolithotomy - always effective and free of complications?].

作者信息

Hentschel H, Janitzky V, Weirich T

机构信息

Klinik für Urologie, Klinikum Pirna GmbH, Schandauer Str., Pirna.

出版信息

Aktuelle Urol. 2007 May;38(3):232-6. doi: 10.1055/s-2006-954978.

Abstract

PURPOSE

The purpose of this study was to evaluate the results and complications of percutaneous nephrolithotomies performed within 5 years in our patients.

MATERIALS AND METHODS

From 2001 to 2005 in our department 158 percutaneous nephrolithotomies (PNL) in 131 patients and 138 renal units were performed. The indications for PNL were calculus greater than 2 cm, failed ESWL, and when there is additional urinary obstruction which was not caused by the stone itself. Data concerning past medical history, about the procedure including complications and the postoperative course were collected and evaluated.

RESULTS

87 (63 %) of the patients had a history of prior stones. The main symptoms were flank pain, recurrent renal colic and urinary tract infection. The stones treated had a size from 5 to 60 mm. In 40 patients (29 %) relief of urinary obstruction (double-J-ureteral stent or percutaneous nephrostomy) or ESWL was performed prior to PNL. Mean operating time was 83 (30 - 235) minutes including retrograde placement of a ureteral catheter and nephrostomy. Complications occurred in 26 (16.5 %) procedures. Severe complications were: one fatal pulmonary embolism, one septicaemia, three open revisions (including one nephrectomy) and four blood transfusions for blood loss. In 94 patients (68 %) there was no residual stone or gravel after the first PNL. No further therapy was necessary in 17 (39 %) of the 44 patients with incomplete stone removal. 19 patients underwent a secondary PNL. In these procedures the efficacy decreased. 102 of 131 patients (138 renal units = 73.9 %) were discharged without residual stone after 158 procedures.

CONCLUSIONS

PNL is an efficient and rarely complicated procedure for larger stones of the upper urinary tract. Even so, the occurrence of severe complications must be considered. Complications can be minimised by the use of a standardised therapeutic pathway.

摘要

目的

本研究旨在评估在我们的患者中5年内进行经皮肾镜取石术的结果及并发症。

材料与方法

2001年至2005年,我们科室对131例患者的138个肾单位进行了158次经皮肾镜取石术(PNL)。PNL的适应证为结石大于2 cm、体外冲击波碎石术(ESWL)失败以及存在非结石本身引起的额外尿路梗阻。收集并评估了有关既往病史、手术相关情况(包括并发症和术后病程)的数据。

结果

87例(63%)患者有既往结石病史。主要症状为胁腹痛、复发性肾绞痛和尿路感染。所治疗的结石大小为5至60 mm。40例(29%)患者在PNL之前进行了尿路梗阻解除(双J输尿管支架或经皮肾造瘘)或ESWL。平均手术时间为83(30 - 235)分钟,包括逆行放置输尿管导管和肾造瘘。26例(16.5%)手术出现并发症。严重并发症包括:1例致命性肺栓塞、1例败血症、3例开放性修复(包括1例肾切除术)以及4例因失血进行输血。94例(68%)患者在首次PNL后无残留结石或碎石。44例结石清除不完全的患者中,17例(39%)无需进一步治疗。19例患者接受了二次PNL。在这些手术中,疗效有所下降。131例患者中的102例(138个肾单位 = 73.9%)在158次手术后无残留结石出院。

结论

PNL是治疗上尿路较大结石的一种有效且并发症少见的手术。即便如此,仍须考虑严重并发症的发生。通过采用标准化治疗路径可将并发症降至最低。

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