Iseli R K, Brand C, Telford M, LoGiudice D
Department of Geriatric Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Intern Med J. 2007 Dec;37(12):806-11. doi: 10.1111/j.1445-5994.2007.01386.x. Epub 2007 May 21.
More than 49% of all US hospital days are spent caring for patients with delirium. There are few Australian data on this important condition. The aim of the study was to determine the prevalence and incidence of delirium in older medical inpatients in a metropolitan teaching hospital, the incidence of known risk factors and current practice in identifying and managing patients at risk of this condition.
Patients aged 65 years or more, and admitted to a general medical unit, were eligible for study inclusion. Participants were screened with an Abbreviated Mental Test Score (AMTS) and chart review. Confusion Assessment Method was used to diagnose delirium if confusion was documented or AMTS < 8. Barthel Index (BI), demographics, delirium risk factors and management were recorded.
Prevalent delirium was diagnosed in 19 of 104 (18%) and incident delirium in 2 of 85 (2%) participants. Pre-existing cognitive impairment and admission AMTS < 8 were strongly associated with prevalent delirium (P-values < 0.01). Age > 80 years, Barthel Index < or = 50, use of high-risk medications and electrolyte disturbance were also associated with prevalent delirium. Prevalent delirium was not recognized by the treating unit in 4 of 19 cases (21%). Five of 104 (4.8%) of participants had a formal cognitive assessment on admission. One of 19 patients (5.3%) with prevalent delirium had an orientation device in their room.
Pre-existing cognitive impairment and admission AMTS are strong predictors of delirium. Despite this, formal cognitive assessment is not routinely carried out in elderly medical patients. Recognition of delirium may be improved by routine cognitive assessment in elderly medical patients.
在美国,超过49%的住院天数用于照料谵妄患者。关于这一重要病症,澳大利亚的数据很少。本研究的目的是确定一家大都市教学医院老年内科住院患者中谵妄的患病率和发病率、已知危险因素的发生率以及识别和管理有此病症风险患者的当前做法。
年龄在65岁及以上且入住普通内科病房的患者符合研究纳入标准。参与者接受简易精神状态检查表(AMTS)筛查和病历审查。如果有精神错乱记录或AMTS<8,则使用谵妄评估方法诊断谵妄。记录巴氏指数(BI)、人口统计学数据、谵妄危险因素和管理情况。
104名参与者中有19名(18%)被诊断为谵妄,85名参与者中有2名(2%)发生谵妄。既往认知障碍和入院时AMTS<8与谵妄密切相关(P值<0.01)。年龄>80岁、巴氏指数≤50、使用高风险药物和电解质紊乱也与谵妄相关。19例中有4例(21%)治疗科室未识别出谵妄。104名参与者中有5名(4.8%)在入院时进行了正式的认知评估。19例谵妄患者中有1例(5.3%)病房内有定向设备。
既往认知障碍和入院时的AMTS是谵妄的有力预测指标。尽管如此,老年内科患者并未常规进行正式的认知评估。对老年内科患者进行常规认知评估可能会提高对谵妄的识别率。