Adjogble Kokou-Louis-Sewonou, Lourd Mathilde, Njanpop-Lafourcade Berthe-Marie, Traoré Yves, Hlomaschi Avoko Fidelia Sitti, Amegatse K Agbenon, Agbenoko Kodjo, Sanou Oumarou, Sita Kroman, Mueller Judith E, Gessner Bradford D
Ministère de la Sante Publique du Togo, Lomé, Togo.
Vaccine. 2007 Sep 3;25 Suppl 1:A47-52. doi: 10.1016/j.vaccine.2007.04.040. Epub 2007 May 7.
Few reports documenting the epidemiology of Neisseria meningitidis (Nm) serogroup W135 exist, and none from Togo. During 2003-2005, we conducted acute bacterial meningitis surveillance at three major reference hospitals in Togo. Of 116 Nm identified, 83 (71%) were NmA, 23 (20%) were NmW135, and 10 (9%) did not have a serogroup identified. Nine percent of NmW135 cases and 35% of NmA cases occurred among those aged 15 years or older. The two hospitals in central Togo reported 23% of all Nm cases and 78% of NmW135 cases. Twelve of the 23 NmW135 cases occurred during February-March 2003, while the remaining 11 occurred sporadically over the remaining 18 months of the study. NmW135 meningitis showed pronounced temporal and geographic clustering and occurred almost exclusively among those younger than 15 years old. By the 2004-2005 epidemic season, NmW135 had largely disappeared from Togo for unknown reasons.
记录脑膜炎奈瑟菌(Nm)W135血清群流行病学情况的报告很少,多哥尚无此类报告。2003 - 2005年期间,我们在多哥的三家主要参考医院开展了急性细菌性脑膜炎监测。在鉴定出的116株Nm中,83株(71%)为Nm A群,23株(20%)为Nm W135群,10株(9%)未鉴定出血清群。15岁及以上人群中,9%的病例为Nm W135群感染,35%的病例为Nm A群感染。多哥中部的两家医院报告了所有Nm病例的23%以及Nm W135病例的78%。23例Nm W135病例中的12例发生在2003年2月至3月,其余11例在研究的剩余18个月中散在发生。Nm W135脑膜炎呈现出明显的时间和地理聚集性,几乎仅发生在15岁以下人群中。到2004 - 2005年流行季节,Nm W135在多哥已基本消失,原因不明。