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简短通讯:饲喂代用初乳的犊牛对蛋白质和免疫球蛋白G的吸收

Short communication: Absorption of protein and immunoglobulin g in calves fed a colostrum replacer.

作者信息

Smith G W, Foster D M

机构信息

Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA.

出版信息

J Dairy Sci. 2007 Jun;90(6):2905-8. doi: 10.3168/jds.2006-682.

Abstract

A well-managed colostrum program on farms is the most important step in reducing disease in neonatal calves. In the last few years, colostrum replacers have increased in popularity and are designed to be an alternative to colostrum on farms that have poor colostrum quality, limited colostrum reserves, or to break the cycle of transmission for certain infectious diseases. However, it is important to make sure these products are effective and are capable of providing adequate serum immunoglobulin concentrations. The objective of this study was to evaluate the efficacy of a commercially available colostrum replacer product in dairy calves. Holstein calves from a single dairy were randomly assigned to 1 of 3 groups at birth. Group 1 (n = 21) calves were given 4 quarts of colostrum via esophageal feeder within 3 h of birth and served as the control group for this study. Group 2 (n = 21) received 2 packages of a colostrum replacer product, and group 3 (n = 21) received 3 packages of the colostrum replacer product within 3 h of birth. Blood samples from all calves were collected 24 h after colostrum administration and analyzed for serum total protein and IgG concentrations. Calves fed fresh colostrum had significantly higher serum total protein levels and IgG concentrations compared with calves fed the colostrum replacer product. Calves fed the colostrum replacer also had a significantly higher percentage of calves with failure of passive transfer (serum IgG <1,000 mg/dL). The colostrum replacer product evaluated in this study failed to routinely provide adequate IgG concentrations when fed according to label directions.

摘要

农场中实施管理良好的初乳计划是降低新生犊牛疾病发生率的最重要步骤。在过去几年中,初乳代用品越来越受欢迎,其设计目的是为初乳质量差、初乳储备有限的农场提供初乳替代品,或打破某些传染病的传播循环。然而,确保这些产品有效并能够提供足够的血清免疫球蛋白浓度非常重要。本研究的目的是评估一种市售初乳代用品产品对奶牛犊牛的功效。来自单个奶牛场的荷斯坦犊牛在出生时被随机分配到3组中的1组。第1组(n = 21)犊牛在出生后3小时内通过食管饲管给予4夸脱初乳,作为本研究的对照组。第2组(n = 21)在出生后3小时内接受2包初乳代用品产品,第3组(n = 21)在出生后3小时内接受3包初乳代用品产品。在给予初乳24小时后采集所有犊牛的血样,分析血清总蛋白和IgG浓度。与喂食初乳代用品产品的犊牛相比,喂食新鲜初乳的犊牛血清总蛋白水平和IgG浓度显著更高。喂食初乳代用品的犊牛被动转移失败(血清IgG <1,000 mg/dL)的比例也显著更高。本研究中评估的初乳代用品产品按照标签说明喂食时未能常规提供足够的IgG浓度。

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