南非德班地区合并耐多药结核病与艾滋病毒共同感染的妊娠情况
Pregnancies complicated by multidrug-resistant tuberculosis and HIV co-infection in Durban, South Africa.
作者信息
Khan M, Pillay T, Moodley J, Ramjee A, Padayatchi N
机构信息
Centre for the AIDS Programme of Research in South Africa, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Congella, Durban, KwaZulu Natal, South Africa.
出版信息
Int J Tuberc Lung Dis. 2007 Jun;11(6):706-8.
SETTING
Tertiary hospitals in KwaZulu Natal, South Africa.
OBJECTIVE
To study the impact of multidrug-resistant tuberculosis (MDR-TB) and human immunodeficiency virus-1 (HIV-1) co-infection during pregnancy on maternal and perinatal outcome.
DESIGN
Prospective study performed between 1996 and 2001. Symptomatic pregnant women were investigated for TB. Those with confirmed MDR-TB were reported on.
RESULTS
Three of five pregnant women with MDR-TB were HIV-1 co-infected. One woman decided to terminate the pregnancy and one experienced pre-term labour. Two neonates had features of growth restriction.
CONCLUSION
Management of pregnant women with MDR-TB in an HIV-endemic area is possible in developing countries.
背景
南非夸祖鲁-纳塔尔省的三级医院。
目的
研究孕期耐多药结核病（MDR-TB）与人类免疫缺陷病毒1型（HIV-1）合并感染对孕产妇和围产期结局的影响。
设计
1996年至2001年间进行的前瞻性研究。对有症状的孕妇进行结核病调查。报告确诊为耐多药结核病的患者。
结果
五名耐多药结核病孕妇中有三名合并感染HIV-1。一名妇女决定终止妊娠，一名经历了早产。两名新生儿有生长受限的特征。
结论
在发展中国家，在艾滋病流行地区对耐多药结核病孕妇进行管理是可行的。
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