Thillagavathie P
Department of Paediatrics and Child Health, Medical School, University of Natal, Congella, Durban, 4013, South Africa.
Semin Neonatol. 2000 Aug;5(3):189-96. doi: 10.1053/siny.2000.0022.
Human immunodeficiency virus type 1 (HIV-1) and tuberculosis (TB) are among the leading causes of disability and death in the developing world, the largest burden borne by sub-Saharan Africa and Asia. Both diseases are significant among women of childbearing age, and TB, although uncommon in pregnancy, is on the increase. While earlier reports were contradictory regarding the effect of TB on the course of pregnancy and vice versa, the negative impacts of each on the other have been documented, some in relation to HIV-1 co-infection. This review focuses on emerging data on maternal and perinatal TB within the context of HIV-1 infection.
人类免疫缺陷病毒1型(HIV-1)和结核病(TB)是发展中世界残疾和死亡的主要原因,撒哈拉以南非洲和亚洲承受着最大的负担。这两种疾病在育龄妇女中都很普遍,结核病虽然在孕期并不常见,但呈上升趋势。虽然早期报告关于结核病对妊娠过程的影响以及反之妊娠对结核病的影响相互矛盾,但两者相互之间的负面影响已有文献记载,其中一些与HIV-1合并感染有关。本综述重点关注HIV-1感染背景下孕产妇和围产期结核病的新数据。