Katati Majed J, Santiago-Ramajo Sandra, Pérez-García Miguel, Meersmans-Sánchez Jofré Miguel, Vilar-Lopez Raquel, Coín-Mejias Maria Angeles, Caracuel-Romero Alfonso, Arjona-Moron Ventura
Neurosurgery Service, Virgen de las Nieves Hospital, Granada, Spain.
Cerebrovasc Dis. 2007;24(1):66-73. doi: 10.1159/000103118. Epub 2007 May 22.
According to previous studies, the quality of life is usually substantially altered in patients who have suffered a subarachnoid hemorrhage of an aneurysmal origin. Some studies have attempted to find out which factors predict the deterioration in quality of life. Our study will try to describe the quality of life of these patients and discover which variables may predict it in each of its dimensions.
The participants were 70 patients with aneurysmal subarachnoid hemorrhage between 15 and 85 years of age. The instrument used to measure the quality of life is the SF-36 with its eight dimensions. The predictor variables introduced into the multiple linear regressions are neurological condition on admission [World Federation of Neurological Surgeons (WFNS) scale and Hunt and Hess scale], extension of the hemorrhage (Fisher scale), sex, age, physical handicaps, and the Glasgow Outcome Scale (GOS) on release.
The results showed that 42.9% of the patients had a deteriorated quality of life after 4 months, and that the most affected dimension was the Physical Role (60%). The two factors that predict quality of life are sex and physical handicaps. Other factors that intervene are the GOS on release and the WFNS.
The patients who have experienced an aneurysmal subarachnoid hemorrhage show greater difficulty in performing daily activities, and they present more depression and anxiety. The absence of handicaps and being male are predictor factors for an unaffected quality of life.
根据以往研究，动脉瘤性蛛网膜下腔出血患者的生活质量通常会发生显著改变。一些研究试图找出哪些因素可预测生活质量的恶化。我们的研究将试图描述这些患者的生活质量，并发现哪些变量在其各个维度上可能对其有预测作用。
研究对象为70例年龄在15至85岁之间的动脉瘤性蛛网膜下腔出血患者。用于测量生活质量的工具是具有八个维度的SF - 36。纳入多重线性回归的预测变量为入院时的神经状况[世界神经外科医师联合会（WFNS）分级和Hunt - Hess分级]、出血范围（Fisher分级）、性别、年龄、身体残疾情况以及出院时的格拉斯哥预后评分（GOS）。
结果显示，42.9%的患者在4个月后生活质量恶化，其中受影响最大的维度是身体功能（60%）。预测生活质量的两个因素是性别和身体残疾情况。其他起作用的因素是出院时的GOS和WFNS。
经历过动脉瘤性蛛网膜下腔出血的患者在进行日常活动时困难更大，且表现出更多的抑郁和焦虑。没有残疾且为男性是生活质量未受影响的预测因素。
