Laska A C, Mårtensson B, Kahan T, von Arbin M, Murray V
Department of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
Cerebrovasc Dis. 2007;24(1):74-9. doi: 10.1159/000103119. Epub 2007 May 23.
Data on post-stroke depression in aphasia are scarce.
Eighty-nine acute stroke patients with aphasia of all types were followed for 6 months to investigate if depression can be reliably diagnosed (DSM-IV criteria) and validly assessed by the verbal Montgomery-Asberg Depression Rating Scale (MADRS) and a global technique (Clinical Global Impressions Rating Scale for Severity). A standard aphasia test was performed.
In 60 patients (67%) at baseline and in 100% at 6 months, comprehension allowed a reliable DSM-IV diagnosis. Among these patients MADRS was feasible in 95% at baseline and in 100% at 6 months. The assistance of relatives and staff increases the feasibility and decreases the validity. Depression was identified in 24% during the 6 months.
Depression diagnosis and severity rating can reliably be made in the acute phase in at least two thirds of aphasic patients, and feasibility increases over time.
关于失语症患者中风后抑郁的数据很少。
对89例各类急性失语症中风患者进行了6个月的随访，以调查是否可以通过言语蒙哥马利-阿斯伯格抑郁评定量表（MADRS）和一种整体技术（临床总体印象严重程度评定量表）可靠地诊断（DSM-IV标准）和有效评估抑郁症。进行了标准失语症测试。
在60例患者（67%）基线时以及100%的患者在6个月时，理解能力允许进行可靠的DSM-IV诊断。在这些患者中，MADRS在基线时95%可行，在6个月时100%可行。亲属和工作人员的协助增加了可行性，但降低了有效性。在6个月期间，24%的患者被确诊患有抑郁症。
至少三分之二的失语症患者在急性期能够可靠地进行抑郁症诊断和严重程度评定，并且随着时间的推移可行性会增加。
