单次癫痫发作是否会导致人类海马神经元死亡？
Do single seizures cause neuronal death in the human hippocampus?
机构信息
Pharmacobiology Department, Center for Research and Advanced Studies, Mexico City, Mexico.
出版信息
Epilepsy Curr. 2007 May-Jun;7(3):77-81. doi: 10.1111/j.1535-7511.2007.00178.x.
Abstract
The question of whether repeated single seizures cause neuronal death in the adult human brain is of great clinical importance and might have broad therapeutic implications. Reviewed here are recent studies on the effects of repeated single seizures (in the absence of status epilepticus) on hippocampal volume and on neuronal death markers in blood and in surgically ablated hippocampi.
摘要
反复单发癫痫是否会导致成人脑神经元死亡，这是一个具有重要临床意义的问题，可能具有广泛的治疗意义。本文回顾了关于反复单发癫痫（无癫痫持续状态）对海马体积和血液及手术切除海马内神经元死亡标志物影响的最新研究。
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