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以皮肤转移作为首发临床症状的肝细胞癌

Cutaneous metastasis from hepatocellular carcinoma as the first clinical sign.

作者信息

Amador Auxiliadora, Monforte Neus García, Bejarano Natalia, Martí Josep, Artigau Eva, Navarro Salvador, Fuster Josep

机构信息

Hepato-Biliary-Pancreatic Surgery Unit, Hospital de Sabadell, Consorci Sanitari Parc Taulí, Catalonia, Barcelona, Spain.

出版信息

J Hepatobiliary Pancreat Surg. 2007;14(3):328-30. doi: 10.1007/s00534-006-1141-1. Epub 2007 May 29.

DOI:10.1007/s00534-006-1141-1
PMID:17520212
Abstract

Hepatocellular carcinoma (HCC) is a tumor whose incidence has been increasing in recent years. The occurrence of cutaneous metastases from HCC, as the first sign of onset, is very unusual. We report a case of cutaneous metastasis from HCC appearing as a shoulder abscess and being the first clinical sign of the disease. We also examined the few published cases, and the diagnosis, treatment, and survival rate for this disease. Metastases of HCC should be included in the differential diagnosis of growing lesions in unusual localizations. Biopsies are required to confirm the diagnosis. The diagnosis of HCC from a cutaneous lesion is very uncommon and is associated with a poor prognosis.

摘要

肝细胞癌(HCC)是一种近年来发病率不断上升的肿瘤。HCC发生皮肤转移作为首发症状非常罕见。我们报告了一例以肩部脓肿形式出现的HCC皮肤转移病例,这是该疾病的首个临床症状。我们还研究了少数已发表的病例,以及该疾病的诊断、治疗和生存率。HCC转移应纳入不寻常部位生长性病变的鉴别诊断中。需要进行活检以确诊。从皮肤病变诊断出HCC非常罕见,且预后较差。

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Cutaneous metastasis from hepatocellular carcinoma as the first clinical sign.以皮肤转移作为首发临床症状的肝细胞癌
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Digital acrometastases as first sign of hepatocellular carcinoma.数字性骨转移作为肝细胞癌的首发表现。
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Cutaneous metastases of hepatocellular carcinoma.肝细胞癌的皮肤转移。
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Life (Basel). 2021 Jun 14;11(6):559. doi: 10.3390/life11060559.
2
A case of hepatocellular carcinoma in an elder man with metastasis to the nasopharynx.一名老年男性肝细胞癌伴鼻咽癌转移病例。
Int J Clin Exp Pathol. 2015 May 1;8(5):5919-23. eCollection 2015.
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Solitary scalp metastasis - a rare presentation of hepatocellular carcinoma.孤立性头皮转移瘤——肝细胞癌的一种罕见表现。
Ann Surg Innov Res. 2015 Jun 9;9:4. doi: 10.1186/s13022-015-0013-2. eCollection 2015.
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Cutaneous manifestations of common liver diseases.常见肝脏疾病的皮肤表现
J Clin Exp Hepatol. 2011 Dec;1(3):177-84. doi: 10.1016/S0973-6883(11)60235-1. Epub 2012 Jan 2.
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Cutaneous Metastases from Primary Hepatobiliary Tumors as the First Sign of Tumor Recurrence following Liver Transplantation.原发性肝胆肿瘤的皮肤转移作为肝移植后肿瘤复发的首发征象
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Leptomeningeal metastasis from hepatocellular carcinoma with other unusual metastases: a case report.肝细胞癌伴其他罕见转移的软脑膜转移:一例报告
BMC Cancer. 2014 Jun 3;14:399. doi: 10.1186/1471-2407-14-399.
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Hepatocellular carcinoma with subcutaneous metastasis of the scalp.头皮皮下转移的肝细胞癌。
Radiol Oncol. 2011 Dec;45(4):292-5. doi: 10.2478/v10019-011-0022-7. Epub 2011 Jul 20.
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Haematogenous abdominal wall metastasis of differentiated, alpha-fetoprotein-negative hepatocellular carcinoma after previous antiandrogen therapy within a site of lipoma manifestation since childhood.儿童期起脂瘤表现部位既往接受抗雄激素治疗后分化型、甲胎蛋白阴性肝细胞癌血源性腹壁转移。
World J Surg Oncol. 2012 May 30;10:98. doi: 10.1186/1477-7819-10-98.
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Hepatocellular carcinoma with cutaneous metastases.伴有皮肤转移的肝细胞癌
Can J Gastroenterol. 2009 Jan;23(1):23-5. doi: 10.1155/2009/274357.