Ooue Anna, Ichinose-Kuwahara Tomoko, Shamsuddin A K M, Inoue Yoshimitsu, Nishiyasu Takeshi, Koga Shunsaku, Kondo Narihiko
Laboratory for Applied Human Physiology, Faculty of Human Development, Kobe University, 3-11 Tsurukabuto, Kobe, Japan.
Eur J Appl Physiol. 2007 Sep;101(1):97-103. doi: 10.1007/s00421-007-0478-8. Epub 2007 May 23.
The purposes of this study were (1) to evaluate changes in blood flow in the brachial artery and basilic vein of the upper arm with a rise in internal temperature during passive heating; and (2) to investigate the contributions of blood velocity and anteroposterior vessel diameter to these blood flow changes. Ten subjects rested in the supine position between a pair of tube-lined sheets. Thermoneutral water was circulated through the tubes to keep a mean skin temperature (Tsk) of 34-35 degrees C, and then hot water was circulated to maintain Tsk of 37-38 degrees C. The blood velocity and diameter in the brachial artery and basilic vein were continuously monitored by Doppler ultrasound technique and used to calculate blood flow. Blood flow in the brachial artery and basilic vein increased linearly as the oral temperature (T(or)) rose by < or =0.6 degrees C. The magnitude of the change in blood flow did not differ significantly between the two vessels. In addition, plots of DeltaT(or) versus blood flow yielded slopes that did not differ significantly between the brachial artery and the basilic vein. As T (or) increased, blood velocity, but not diameter, also increased. In conclusion, blood flow in the brachial artery and the basilic vein increased linearly as the internal temperature variable T (or) increased < or =0.6 degrees C. In both vessels, the passive heating-induced increases in blood flow resulted primarily from a change in blood velocity, rather than from a change in diameter.
（1）评估被动加热期间随着体内温度升高，上臂肱动脉和贵要静脉的血流变化；（2）研究血流速度和血管前后径对这些血流变化的影响。10名受试者仰卧于一对衬有管子的床单之间。通过管子循环热中性水以保持平均皮肤温度（Tsk）为34 - 35摄氏度，然后循环热水以维持Tsk为37 - 38摄氏度。采用多普勒超声技术持续监测肱动脉和贵要静脉的血流速度和直径，并用于计算血流量。随着口腔温度（T(or)）升高≤0.6摄氏度，肱动脉和贵要静脉的血流量呈线性增加。两条血管血流量变化的幅度无显著差异。此外，ΔT(or)与血流量的关系图显示，肱动脉和贵要静脉的斜率无显著差异。随着T(or)升高，血流速度增加，而血管直径未增加。总之，随着体内温度变量T(or)升高≤0.6摄氏度，肱动脉和贵要静脉的血流量呈线性增加。在这两条血管中，被动加热引起的血流量增加主要是由血流速度变化导致的，而非血管直径变化。
