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肝移植术后胆管狭窄的磁共振胰胆管造影:一项前瞻性双盲研究。

Magnetic resonance cholangiography of biliary strictures after liver transplantation: a prospective double-blind study.

作者信息

Kitazono Mary T, Qayyum Aliya, Yeh Benjamin M, Chard Paul S, Ostroff James W, Coakley Fergus V

机构信息

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

出版信息

J Magn Reson Imaging. 2007 Jun;25(6):1168-73. doi: 10.1002/jmri.20927.

DOI:10.1002/jmri.20927
PMID:17520726
Abstract

PURPOSE

To compare magnetic resonance cholangiography (MRC) with endoscopic retrograde cholangiography (ERC) in quantitatively evaluating biliary strictures in liver transplant recipients.

MATERIALS AND METHODS

Eight liver transplant recipients with suspected biliary complications were referred for ERC and also underwent MRC within 24 hours using a combination of single-shot rapid acquisition with relaxation enhancement (SS-RARE) and three-dimensional (3D)-RARE sequences. The studies were independently interpreted by two blinded radiologists and a single blinded endoscopist who recorded the presence of a stricture and/or upstream dilatation, the ratio of recipient-to-donor duct diameters at the anastomosis, as well as the proximal duct diameter, length, and percent stenosis of any stricture detected.

RESULTS

Using ERC as the standard of reference, MRC had a sensitivity and negative predictive value of 100%, mean specificity of 83.3%, and mean positive predictive value of 92.9% in the detection of six strictures. Compared with ERC, MRC obtained accurate measurements of recipient-to-donor duct diameter ratios (r, 0.91; P < 0.01), proximal duct diameters (r, 0.83, P < 0.05), stricture lengths (r, 0.58; P = 0.06), and percent stenosis (r, 0.78; P = 0.06).

CONCLUSION

MRC can provide equivalent imaging to ERC and can reliably identify and quantitatively evaluate biliary strictures in post-orthotopic liver transplantation (OLT) patients.

摘要

目的

比较磁共振胆胰管造影(MRC)与内镜逆行胰胆管造影(ERC)在定量评估肝移植受者胆管狭窄方面的效果。

材料与方法

8例疑似胆管并发症的肝移植受者接受了ERC检查,并在24小时内采用单次激发快速采集弛豫增强序列(SS-RARE)和三维(3D)-RARE序列联合进行了MRC检查。两名放射科医生和一名内镜医生分别对检查结果进行独立解读,记录狭窄和/或上游扩张的情况、吻合口处受者与供者胆管直径的比例,以及检测到的任何狭窄的近端胆管直径、长度和狭窄百分比。

结果

以ERC作为参考标准,MRC在检测6处狭窄时,敏感性和阴性预测值均为100%,平均特异性为83.3%,平均阳性预测值为92.9%。与ERC相比,MRC获得了受者与供者胆管直径比(r,0.91;P<0.01)、近端胆管直径(r,0.83,P<0.05)、狭窄长度(r,0.58;P = 0.06)和狭窄百分比(r,0.78;P = 0.06)的准确测量值。

结论

MRC能提供与ERC相当的成像,可可靠地识别和定量评估原位肝移植(OLT)术后患者的胆管狭窄。

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