Gentilini Oreste, Chagas Eduardo, Zurrida Stefano, Intra Mattia, De Cicco Concetta, Gatti Giovanna, Silva Luzemira, Renne Giuseppe, Cassano Enrico, Veronesi Umberto
Division of Breast Surgery, European Institute of Oncology, 20141, Milan, Italy.
Oncologist. 2007 May;12(5):512-5. doi: 10.1634/theoncologist.12-5-512.
Mastectomy with axillary dissection is still the most commonly recommended procedure for male breast cancer. The aim of this study was to retrospectively evaluate our experience in 32 male patients with early breast cancer who underwent sentinel lymph node biopsy (SLNB) and axillary dissection only in cases of metastases in the sentinel lymph node (SLN). The median age was 58 years (range, 33-80). Lymphoscintigraphy was successful in all patients, with a mean number of visualized SLNs per patient of 1.3 (range, 1-2). At surgery, the identification rate of the SLN was 100%, with a mean number of removed SLNs per patient of 1.5 (range, 1-3). Twenty-six patients had negative SLNs, six patients had positive SLNs. Two patients with metastatic SLNs had additional positive nodes. After a median follow-up of 30 months (range, 1-63) no axillary reappearance of the disease occurred. As with women, we recommend SLNB in male patients with breast cancer and clinically negative axilla.
乳房切除术加腋窝清扫术仍是男性乳腺癌最常推荐的手术方式。本研究的目的是回顾性评估我们对32例早期乳腺癌男性患者的经验，这些患者仅在前哨淋巴结（SLN）发生转移时才进行前哨淋巴结活检（SLNB）和腋窝清扫术。中位年龄为58岁（范围33 - 80岁）。所有患者淋巴闪烁显像均成功，每位患者可视化SLN的平均数量为1.3个（范围1 - 2个）。手术时，SLN的识别率为100%，每位患者切除的SLN平均数量为1.5个（范围1 - 3个）。26例患者SLN阴性，6例患者SLN阳性。2例SLN转移患者有额外的阳性淋巴结。中位随访30个月（范围1 - 63个月）后，腋窝未出现疾病复发。与女性患者一样，我们建议对乳腺癌且临床腋窝阴性的男性患者进行SLNB。
