Ilhan Enver, Bati Bakir, Alemdar Ali, Coskun Ali, Sezgin Arsenal, Yildirim Mehmet, Engin Omer, Purten Mete
Department of General Surgery, Izmir Bozyaka Education and Research Hospital, Turkey.
Department of General Surgery, Istanbul Okmeydani Education and Research Hospital, Turkey.
Breast Care (Basel). 2009 Nov;4(5):308-314. doi: 10.1159/000230912. Epub 2009 Oct 1.
Although male breast cancer constitutes only 1% of all breast cancers, its incidence is increasing and it is becoming an important public health issue. The present study aims to present the clinicopathological characteristics of surgically treated male breast cancer patients from multiple centers.
Twenty-one male patients operated on for breast cancer were retrospectively examined in terms of clinical presentation, pathological characteristics, TNM staging status, and type of surgical treatment.
The mean age of the 21 patients was 62.3 years (range 38-94), with the majority being in the range of 50-69 years (61.9%). The most frequent finding was breast mass (85.7%). Most patients underwent modified radical mastectomy (76.1%), and the most prevalent histological type was invasive ductal carcinoma (85.7%). The majority of patients had stage II or III disease, and estrogen receptors were positive in 18 (85.7%) of the patients.
Since male breast cancer is a rare condition, it is challenging to conduct prospective randomized trials. Currently, there is a lack of comprehensive data on the diagnosis and management of this condition. Thus, further studies and the implementation of specific guidelines or protocols for this subgroup of patients will aid better management.
尽管男性乳腺癌仅占所有乳腺癌的1%，但其发病率正在上升，正成为一个重要的公共卫生问题。本研究旨在呈现来自多个中心的接受手术治疗的男性乳腺癌患者的临床病理特征。
对21例接受乳腺癌手术的男性患者的临床表现、病理特征、TNM分期情况及手术治疗类型进行回顾性研究。
21例患者的平均年龄为62.3岁（范围38 - 94岁），大多数患者年龄在50 - 69岁之间（61.9%）。最常见的表现是乳房肿块（85.7%）。大多数患者接受了改良根治性乳房切除术（76.1%），最常见的组织学类型是浸润性导管癌（85.7%）。大多数患者患有II期或III期疾病，18例（85.7%）患者的雌激素受体呈阳性。
由于男性乳腺癌是一种罕见疾病，开展前瞻性随机试验具有挑战性。目前，关于这种疾病的诊断和管理缺乏全面的数据。因此，针对该亚组患者进一步开展研究并实施特定的指南或方案将有助于更好地进行管理。
