Leong Ian Y, Farrell Michael J, Helme Robert D, Gibson Stephen J
Department of Geriatric Medicine, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.
J Gerontol A Biol Sci Med Sci. 2007 May;62(5):550-5. doi: 10.1093/gerona/62.5.550.
Aging is associated with greater risk for many illnesses and the prospect of multiple, concurrent disease states. Chronic pain is also very common in advanced age, and there is likely to be a relationship with comorbid burden, but few studies have examined this issue. This study tests the hypothesis that comorbid burden is associated with greater levels of self-reported pain and associated disturbance in mood and function.
Psychometric and medical data were collected from 562 patients (mean age = 76.3 years) attending a geriatric pain clinic. The number of categories endorsed on the Cumulative Illness Rating Scale (CIRS) score was used to measure accumulated comorbid burden. These groups were tested for differences in the severity of self-reported pain. The predictive capacity of comorbid burden for explaining variance in mood disturbance and functional disability was assessed after controlling for any differences in age and severity of pain.
Over 50% of the sample had three or more comorbid problems. Groups with greater levels of comorbidity scored higher on the Present Pain Intensity Index, the sensory and affective subscales of the McGill Pain Questionnaire. Multiple regression analysis showed that the CIRS score explained a significant proportion of the variance in scores on the Geriatric Depression Scale (4.1%), Human Activities Profile (4.8%), and the physical domain of the Sickness Impact Profile (5.9%).
Greater levels of comorbidity are associated with reports of more severe pain, more depressive symptoms, reduced activity levels, and higher physical impact from pain.
衰老与许多疾病的较高风险以及多种并发疾病状态的可能性相关。慢性疼痛在老年人群中也非常常见,并且可能与共病负担有关,但很少有研究探讨这个问题。本研究检验了以下假设:共病负担与自我报告的疼痛程度更高以及情绪和功能方面的相关困扰有关。
从一家老年疼痛诊所的562名患者(平均年龄 = 76.3岁)收集了心理测量和医学数据。累积疾病评定量表(CIRS)评分中认可的类别数量用于衡量累积的共病负担。对这些组进行自我报告疼痛严重程度的差异测试。在控制年龄和疼痛严重程度的任何差异后,评估共病负担对解释情绪困扰和功能残疾差异的预测能力。
超过50%的样本有三个或更多的共病问题。共病程度较高的组在当前疼痛强度指数、麦吉尔疼痛问卷的感觉和情感子量表上得分更高。多元回归分析表明,CIRS评分解释了老年抑郁量表得分(4.1%)、人类活动概况得分(4.8%)和疾病影响概况身体领域得分(5.9%)中相当大比例的方差。
更高的共病程度与更严重的疼痛报告、更多的抑郁症状、活动水平降低以及疼痛对身体的更大影响有关。