Kinner Sonja, Kuehle Christiane A, Langhorst Jost, Ladd Susanne C, Nuefer Michael, Zoepf Thomas, Barkhausen Joerg, Gerken Guido, Lauenstein Thomas C
Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany.
Eur Radiol. 2007 Sep;17(9):2286-93. doi: 10.1007/s00330-007-0643-9. Epub 2007 May 24.
The aim of this study was to compare optical colonoscopy to fecal-tagging-based MR colonography in a screening population in terms of comfort and acceptance ratings as well as for future preferences as colorectal cancer screening examinations. Two hundred eighty-four asymptomatic patients (mean age 59 years) underwent MRC and OC within 4 weeks. While MRC was based on a fecal tagging technique, OC was performed after bowel cleansing. For OC, sedatives and analgesics were used. Patients evaluated both modalities and certain aspects of the examination according to a 10-point-scale with higher scores denoting a worse experience. Furthermore, preferences for future examinations were evaluated. No significant difference was noted for the overall acceptance of OC (mean value 3.0) and MRC (mean value 3.4). For MRC, the placement of the rectal tube was rated as the most unpleasant part, whereas bowel purgation was regarded most inconvenient for OC. Patients aged 55 years and older perceived most aspects less unpleasant than younger patients. Of the patients, 46% preferred MRC for future screening examinations (OC: 44%). OC and MRC have comparable general acceptance levels in a screening population. Especially for patients declining endoscopy as a screening method MRC may evolve as an attractive alternative.
本研究的目的是在筛查人群中，就舒适度、接受度评分以及作为结直肠癌筛查检查的未来偏好方面，比较光学结肠镜检查与基于粪便标记的磁共振结肠成像。284名无症状患者（平均年龄59岁）在4周内接受了磁共振结肠成像（MRC）和光学结肠镜检查（OC）。MRC基于粪便标记技术，而OC在肠道清洁后进行。对于OC，使用了镇静剂和镇痛药。患者根据10分制对两种检查方式及检查的某些方面进行评估，分数越高表示体验越差。此外，还评估了对未来检查的偏好。OC（平均值3.0）和MRC（平均值3.4）的总体接受度无显著差异。对于MRC，直肠管的放置被评为最不愉快的部分，而肠道清洗被认为是OC最不方便的部分。55岁及以上的患者认为大多数方面比年轻患者的不愉快程度更低。在患者中，46%的人未来筛查检查更喜欢MRC（OC：44%）。在筛查人群中，OC和MRC具有相当的总体接受水平。特别是对于拒绝将内镜检查作为筛查方法的患者，MRC可能会成为一种有吸引力的替代方法。
