[巴马科儿童脑型疟疾期间的黑水热：3例报告]
[Blackwater fever in children during cerebral malaria: 3 case reports in Bamako].
作者信息
Oumar A A, Poudiougou B, Sylla M, Sall A, Konate S, Togo B, Diakite M, Keita M M
机构信息
Département d'épidémiologie des affections parasitaires, faculty of medicine, pharmacy and odontostomatology, BP 1805, Bamako, Mali.
出版信息
Arch Pediatr. 2007 Aug;14(8):993-5. doi: 10.1016/j.arcped.2007.04.005. Epub 2007 May 23.
BACKGROUND
Blackwater fever is a rare but serious form of malaria in children. Diagnosis relies on clinical symptoms and on the color of the urines.
OBJECTIVES
To describe blackwater fever in children, a disease whose prevalence seems to be increasing.
METHOD
We report 3 cases of blackwater fever observed in our institution.
RESULTS
In 2 cases, acute renal insufficiency with oligoanuria was observed. In all the 3 cases, treatment with quinine was stopped and replaced by injectable artemether. Evolution was dependent on renal function, and included in 1 patient neurological sequels consisting in aphasia.
CONCLUSION
Blackwater fever is a severe affection whose diagnosis should be evoked using the color of urine. Evolution is usually favorable in the pediatric population, when adequate care can be provided.
背景
黑水热是儿童疟疾中一种罕见但严重的形式。诊断依赖于临床症状和尿液颜色。
目的
描述儿童黑水热这一患病率似乎在上升的疾病。
方法
我们报告在本机构观察到的3例黑水热病例。
结果
2例出现急性肾功能不全伴少尿。3例均停用奎宁治疗，改用注射用蒿甲醚。病情演变取决于肾功能，1例患者出现失语的神经后遗症。
结论
黑水热是一种严重疾病，应根据尿液颜色考虑诊断。在儿科人群中，若能提供充分治疗，病情通常预后良好。
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