Noorbala M-H, Rafati-Shaldehi H, Azizabadi-Farahani M, Assari S
Nephrology/Urology Research Center (NURC), Kidney Transplant Department, Baqiyatallah Medical Sciences University, Tehran, Iran.
Transplant Proc. 2007 May;39(4):923-6. doi: 10.1016/j.transproceed.2007.03.094.
In this study, we have reported updated statistics of the Iranian Transplantation Registry, the status of the recipients and grafts, and a detailed time trend with respect to patient characteristics.
We retrospectively reviewed the Iranian Renal Transplantation Registry and information from the Dialysis and Transplant Patients Public Association, to obtain data on all kidney transplantations performed in Iran between 1986 and 2005. Data were gathered regarding the total number of transplantations, graft loss, recipient death, and donor and recipient characteristics, including demographic data, cause of end-stage renal disease (ESRD), and source of kidney. We assessed changes in variables on a biannual basis.
A total of 19521 transplantations were registered over the study period, of which, 761 recipients (3.9%) had died and 2333 allografts (11.9%) had been lost. The source of the kidney in 2556 (13%) subjects was a living related donor (LRD), in 16234 (83%) a living unrelated donor (LURD), and in 831 (4%) cadaveric. During the study decades we noted an increase in the number of kidney transplantations (from 22 to 3690), age of recipients (from 30 to 40), male-to-female ratio of recipients (from 0.58 to 0.67), male-to-female ratio of donors (from 0.48 to 0.52), diabetes mellitus (from 0% to 27%), and hypertension (from 4% to 15%), as causes of ESRD, as well as the use of cadaveric kidneys (0% to 11%).
Analyzing renal transplantation data not only helps to evaluate the effectiveness of transplantation activities in a country, but also provides information to estimate future costs in the health care system.
在本研究中，我们报告了伊朗移植登记处的最新统计数据、受者和移植物的状况，以及关于患者特征的详细时间趋势。
我们回顾性地查阅了伊朗肾脏移植登记处以及透析和移植患者公共协会的信息，以获取1986年至2005年期间在伊朗进行的所有肾脏移植的数据。收集了关于移植总数、移植物丢失、受者死亡以及供者和受者特征的数据，包括人口统计学数据、终末期肾病（ESRD）的病因以及肾脏来源。我们每半年评估一次变量的变化。
在研究期间共登记了19521例移植，其中761例受者（3.9%）死亡，2333例同种异体移植物（11.9%）丢失。2556例（13%）受试者的肾脏来源为活体亲属供者（LRD），16234例（83%）为活体非亲属供者（LURD），831例（4%）为尸体供者。在研究的几十年间，我们注意到肾脏移植数量（从22例增加到3690例）、受者年龄（从30岁增加到40岁）、受者男女比例（从0.58增加到0.67）、供者男女比例（从0.48增加到0.52）、作为ESRD病因的糖尿病（从0%增加到27%）和高血压（从4%增加到15%）以及尸体肾脏的使用（从0%增加到11%）均有所增加。
分析肾脏移植数据不仅有助于评估一个国家移植活动的有效性，还能为估算医疗保健系统未来的成本提供信息。
