Khosravi M, Bastani B
Department of Internal Medicine, Division of Nephrology, Gilan University of Medical Sciences, Gilan, Iran.
Transplant Proc. 2007 May;39(4):1263-6. doi: 10.1016/j.transproceed.2007.03.036.
We present the case of a 43-year-old renal transplant patient who presented with fever, malaise, pruritus, headache, and severe jaundice of 3-week duration following work in a rice field. He was found to have acute renal failure and severe hyperbilirubinemia with a positive serum leptospira antibody titer, making the diagnosis of Weil's disease. The patient responded to reduction in immunosuppressive medications and intravenous penicillin therapy with no need for dialysis. This is the second case of leptospirosis in a kidney transplant patient reported in the English literature.
我们报告了一例43岁的肾移植患者,该患者在稻田劳作后出现发热、不适、瘙痒、头痛以及持续3周的严重黄疸。他被发现患有急性肾衰竭和严重高胆红素血症,血清钩端螺旋体抗体滴度呈阳性,从而诊断为韦尔病。患者通过减少免疫抑制药物剂量和静脉注射青霉素治疗后病情好转,无需进行透析。这是英文文献中报道的第二例肾移植患者感染钩端螺旋体病的病例。