Poveda Velasco A, Casado Herráez A, Cervantes Ruipérez A, Gallardo Rincón D, García García E, González Martín A, López García G, Mendiola Fernández C, Ojeda González B
Servicio de Oncología Médica, Fundación Instituto Valenciano de Oncología, Valencia, Spain.
Clin Transl Oncol. 2007 May;9(5):308-16. doi: 10.1007/s12094-007-0058-8.
National and international specialists have met with the aim of writing down the guidelines for the treatment of epithelial ovarian cancer (in the Spanish Castilian language). These guidelines are based on the International Consensus that was published in English in the Annals of Oncology in 2005. This condition is the leading cause of death from gynaecological cancer in western countries. Its low rate of survival, barely 30% at 5 years, is above all due to late diagnosis and inappropriate surgery, so emphasis is put on these aspects. After describing the methodology for early detection and a scheme of surgical diagnostic procedures in view of the staging of an ovarian mass, the following therapeutic strategies will be recommended: cytoreductive surgery together with platinum chemotherapy under normal conditions, and also in the case of relapse. Likewise, very recent models of treatment focused on molecular targets are presented, and a broad section on methodology of clinical assays. As for this, co-operation among groups is crucial in order to make the conclusions of these studies valid for the development of new therapies.
国内和国际专家齐聚一堂，旨在撰写上皮性卵巢癌治疗指南（西班牙语）。这些指南基于2005年发表在《肿瘤学年鉴》上的英文国际共识。这种疾病是西方国家妇科癌症的主要死因。其生存率较低，5年生存率仅勉强达到30%，主要原因是诊断延迟和手术不当，因此重点关注这些方面。在描述了早期检测方法以及针对卵巢肿块分期的手术诊断程序方案后，将推荐以下治疗策略：在正常情况下以及复发时进行减瘤手术并联合铂类化疗。同样，还介绍了聚焦分子靶点的最新治疗模式，以及临床检测方法的广泛章节。就此而言，各团队之间的合作对于使这些研究结论对新疗法的开发有效至关重要。
