碳酸饮料与慢性肾脏病
Carbonated beverages and chronic kidney disease.
作者信息
Saldana Tina M, Basso Olga, Darden Rebecca, Sandler Dale P
机构信息
Epidemiology Branch, National Institute of Environmental Health Sciences (NIEHS), NIH, DHHS, Research Triangle Park, NC 27709, USA.
出版信息
Epidemiology. 2007 Jul;18(4):501-6. doi: 10.1097/EDE.0b013e3180646338.
Abstract
BACKGROUND
Carbonated beverage consumption has been linked with diabetes, hypertension, and kidney stones, all risk factors for chronic kidney disease. Cola beverages, in particular, contain phosphoric acid and have been associated with urinary changes that promote kidney stones.
METHODS
We examined the relationship between carbonated beverages (including cola) and chronic kidney disease, using data from 465 patients with newly diagnosed chronic kidney disease and 467 community controls recruited in North Carolina between 1980 and 1982.
RESULTS
Drinking 2 or more colas per day was associated with increased risk of chronic kidney disease (adjusted odds ratio = 2.3; 95% confidence interval = 1.4-3.7). Results were the same for regular colas (2.1; 1.3-3.4) and artificially sweetened colas (2.1; 0.7-2.5). Noncola carbonated beverages were not associated with chronic kidney disease (0.94; 0.4-2.2).
CONCLUSIONS
These preliminary results suggest that cola consumption may increase the risk of chronic kidney disease.
摘要
背景
碳酸饮料的消费与糖尿病、高血压和肾结石有关，这些都是慢性肾脏病的危险因素。特别是可乐饮料含有磷酸，并与促进肾结石形成的尿液变化有关。
方法
我们利用1980年至1982年在北卡罗来纳州招募的465例新诊断慢性肾脏病患者和467例社区对照的数据，研究了碳酸饮料（包括可乐）与慢性肾脏病之间的关系。
结果
每天饮用2杯或更多可乐与慢性肾脏病风险增加相关（校正比值比=2.3；95%置信区间=1.4-3.7）。常规可乐（2.1；1.3-3.4）和人工甜味可乐（2.1；0.7-2.5）的结果相同。非可乐碳酸饮料与慢性肾脏病无关（0.94；0.4-2.2）。
结论
这些初步结果表明，饮用可乐可能会增加慢性肾脏病的风险。
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