Imrie F R, Cox A, Foot B, Macewen C J
Department of Ophthalmology, Ninewells Hospital and Medical School, Dundee, UK.
Eye (Lond). 2008 Sep;22(9):1141-7. doi: 10.1038/sj.eye.6702868. Epub 2007 May 25.
To estimate the incidence of penetrating injuries with retained intraocular foreign bodies (IOFBs) in the United Kingdom, and to provide epidemiological data on the aetiology, management, and visual outcome of such injuries.
Cases were identified prospectively by active surveillance through the British Ophthalmological Surveillance Unit reporting card system, for the 12-month period June 2004 to May 2005 inclusive. Questionnaire data were obtained from UK ophthalmologists at presentation and 6 months following presentation.
Data were available on 97 patients at presentation and 95 patients at follow-up. The minimum estimated incidence of IOFBs in the United Kingdom identified in this study was 0.16 per 100 000. All patients were male. Hammering was the most common mechanism of injury, occurring in 62% of patients. The IOFB was found in the anterior segment in 24%, the posterior segment in 73%, and involved both segments in 3%. Endophthalmitis was diagnosed in 9% of patients. Best-corrected visual acuity of the injured eye at final follow-up was 6/12 or better in 67%, 6/18 to 6/60 in 11%, and worse than 6/60 in 22%. Prognostic factors for a poor visual outcome included poor visual acuity at presentation, prolapse of intraocular tissue, development of endophthalmitis, development of retinal detachment, and large size of IOFB.
The incidence of IOFB in the United Kingdom appears to have reduced compared to previous studies. The majority of patients (67%) retain good visual acuity in the injured eye; however, a significant minority (22%) sustain long-term severe visual loss.
评估英国眼内异物(IOFB)留存的穿透性眼外伤的发病率,并提供有关此类损伤的病因、治疗及视力预后的流行病学数据。
通过英国眼科监测单位报告卡系统进行主动监测,前瞻性地识别2004年6月至2005年5月这12个月期间的病例。在患者就诊时及就诊后6个月从英国眼科医生处获取问卷数据。
有97例患者就诊时的数据以及95例患者随访时的数据。本研究确定的英国IOFB的最低估计发病率为每10万人0.16例。所有患者均为男性。锤击是最常见的致伤机制,62%的患者由此受伤。24%的患者眼内异物位于眼前段,73%位于眼后段,3%累及两个眼段。9%的患者被诊断为眼内炎。最终随访时患眼的最佳矫正视力为6/12或更好的患者占67%,6/18至6/60的占11%,低于6/60的占22%。视力预后差的预后因素包括就诊时视力差、眼内组织脱垂、眼内炎的发生、视网膜脱离的发生以及眼内异物体积大。
与先前的研究相比,英国眼内异物的发病率似乎有所降低。大多数患者(67%)患眼保持良好视力;然而,有相当一部分患者(22%)长期严重视力丧失。