Xie Sheng, Liang Jian, Yan Chun-yan
Department of Gastroenterology, Liuzhou Hospital of Traditional Chinese Medicine, Guangxi.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Apr;27(4):355-8.
To observe the clinical effects and possible mechanism of acupoint drug-finger pressing (ADFP) on gastroesophageal reflux (GER).
Eighty patients were randomly assigned to the treatment group and the control group, 40 in each group. The treatment group was treated by ADFP on Ganshu (BL18), Danshu (BL19), Weishu (BL21) and Pishu (BL20) acupoint of bilateral Foot-taiyang Bladder Meridians with pressing and kneading maneuver for 15 min each time, twice per day, while the control group was treated with acid-inhibitory and gastrokinetic drugs as omeprazole enteric-coated tablets (20 mg, once administration at a 12-h interval) and cisapride tablets (10 mg, thrice daily, taken 15 min before meals). The treatment course for both was 3 weeks.
The symptom score and esophageal pressure obviously decreased (P < 0.05), esophageal pressure was relieved remarkably (P < 0.05) in both groups after treatment with insignificant difference between the groups (P > 0.05). The ratio of 24-h esophageal reflux times and total reflux time, the times of reflux lasting for more than 5 min and the maximum reflux time were all lowered obviously in all patients after treatment, and the improvements was significantly different between the two groups (P < 0.05). Upper gastrointestinal endoscopy suggested obvious amelioration in esophagitis. The total effective rate was 97.5% in the treatment group, significantly higher than that in the control group (80.0%) (P < 0.05). And no obvious adverse reaction was found.
Therapy of ADFP provides a new approach for GER treatment with TCM characteristics, prominent effects and less adverse reaction, and is easily be accepted by patients, so, it is worthy to be generalized.
观察穴位药物指压法(ADFP)治疗胃食管反流(GER)的临床疗效及可能机制。
将80例患者随机分为治疗组和对照组,每组40例。治疗组采用双侧足太阳膀胱经的肝俞(BL18)、胆俞(BL19)、胃俞(BL21)和脾俞(BL20)穴位进行穴位药物指压法治疗,每次按压揉动15分钟,每天2次,而对照组采用抑酸和促胃肠动力药物治疗,如奥美拉唑肠溶胶囊(20毫克,每12小时给药1次)和西沙必利片(10毫克,每日3次,饭前15分钟服用)。两组的疗程均为3周。
两组治疗后症状评分和食管压力均明显降低(P < 0.05),食管压力明显缓解(P < 0.05),组间差异无统计学意义(P > 0.05)。所有患者治疗后24小时食管反流次数与总反流时间的比值、反流持续时间超过5分钟的次数及最大反流时间均明显降低,两组改善情况差异有统计学意义(P < 0.05)。上消化道内镜检查提示食管炎明显改善。治疗组总有效率为97.5%,明显高于对照组(80.0%)(P < 0.05)。且未发现明显不良反应。
穴位药物指压法为GER的治疗提供了一种具有中医特色、疗效显著且不良反应少的新方法,易于被患者接受,值得推广。