Nusier Mohamad K, Bataineh Hameed N, Daradkah Haytham M
Department of Biochemistry and Molecular Biology, Jordan University of Science and Technology, School of Medicine, Irbid 22110, Jordan.
Exp Biol Med (Maywood). 2007 Jun;232(6):809-13.
Ingestion of rosemary (Rosmarinus officinalis L.) by two groups of adult Sprague-Dawley rats at levels of 250 and 500 mg/kg body wt for 63 days was investigated for its effects on fertility. Body weight and absolute and relative testes weights were not affected, but the average weights of epididymides, ventral prostates, seminal vesicles, and preputial glands decreased significantly. A significant decline in spermatogenesis in testes due to a decrease in the number of primary and secondary spermatocytes and spermatids in treatment group 2 (500 mg/kg) is attributed to a significant decrease in testosterone. Sperm motility and density were also significantly decreased in the cauda epididymis and in the testes of rosemary-treated male rats in group 2. In addition, the treatment markedly increased the number of fetal resorptions in female rats impregnated by group 2 males, thereby reducing their fertility.
研究了两组成年斯普拉格-道利大鼠以250和500毫克/千克体重的剂量摄入迷迭香（迷迭香叶）63天对其生育能力的影响。体重以及绝对和相对睾丸重量未受影响，但附睾、腹侧前列腺、精囊和包皮腺的平均重量显著下降。由于治疗组2（500毫克/千克）中初级和次级精母细胞以及精子细胞数量减少，睾丸中的精子发生显著下降，这归因于睾酮的显著降低。迷迭香处理的第2组雄性大鼠的附睾尾部和睾丸中的精子活力和密度也显著降低。此外，该处理显著增加了由第2组雄性大鼠使雌性大鼠受孕后的胎儿吸收数量，从而降低了它们的生育能力。
