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慢性阻塞性肺疾病急性加重期患者动脉血气分析与静脉血气分析的比较

Comparison of arterial and venous blood gases analysis in patients with exacerbation of chronic obstructive pulmonary disease.

作者信息

Razi Ebrahim, Moosavi Gholam A

机构信息

Kashan University of Medical Sciences, Kashan, Iran.

出版信息

Saudi Med J. 2007 Jun;28(6):862-5.

PMID:17530100
Abstract

OBJECTIVE

To investigate whether venous blood gases (VBG) test can be replace by an arterial blood gases (ABG) in exacerbation of chronic obstructive pulmonary disease (COPD).

METHODS

From October 2005 to March 2006, at the Emergency Room of Kashan Beheshti Hospital, the data of 107 patients with exacerbation of COPD were assessed. Arterial blood gases and VBG samples were obtained simultaneously, and indexes of pH, carbon dioxide partial pressure (PCO2), bicarbonate (HCO3), oxygen partial pressure (PO2) and Oxygen (O2) saturation level were analyzed.

RESULTS

The mean +/- SD of indexes in ABG and VBG samples were as follows: pH = 7.37 +/- 0.47 versus 7.34 +/- 0.047; PCO2 = 53.88 +/- 7.63 mm Hg versus 59.55 +/- 8.96 mm Hg, HCO3= 30.66 +/- 4.49 mEq/L versus 31.94 +/- 4.39 mEq/L; PO2 = 55.37 +/- 11.19 mm Hg versus 43.08 +/- 10.54 mm Hg. The average difference between indexes in ABG and VBG samples were as follows: pH = 0.0241 +/- 0.004, p<0.001, r = 0.864; PCO2 = 5.673 +/- 1.126 mm Hg, p<0.001, r = 0.761; HCO3 = 1.279 +/- 0.604 mEq/L, p<0.001, r = 0.749; and PO2 = 12.294 +/- 2.115 mm Hg, p<0.001, r = 0.702.

CONCLUSION

Venous blood gases, especially pH and PCO2 levels have relatively good correlation with ABG values. In view of the fact that, this correlation is not close, VBG cannot be substitute for ABG in exacerbation of COPD.

摘要

目的

探讨在慢性阻塞性肺疾病(COPD)急性加重期,静脉血气(VBG)检测是否可被动脉血气(ABG)检测所替代。

方法

2005年10月至2006年3月,在卡尚贝赫什蒂医院急诊科,对107例COPD急性加重期患者的数据进行评估。同时采集动脉血气和VBG样本,并分析pH值、二氧化碳分压(PCO2)、碳酸氢盐(HCO3)、氧分压(PO2)和氧(O2)饱和度水平等指标。

结果

ABG和VBG样本中各指标的均值±标准差如下:pH = 7.37±0.47对比7.34±0.047;PCO2 = 53.88±7.63 mmHg对比59.55±8.96 mmHg,HCO3 = 30.66±4.49 mEq/L对比31.94±4.39 mEq/L;PO2 = 55.37±11.19 mmHg对比43.08±10.54 mmHg。ABG和VBG样本中各指标的平均差值如下:pH = 0.0241±0.004,p<0.001,r = 0.864;PCO2 = 5.673±1.126 mmHg,p<0.001,r = 0.761;HCO3 = 1.279±0.604 mEq/L,p<0.001,r = 0.749;PO2 = 12.294±2.115 mmHg,p<0.001,r = 0.702。

结论

静脉血气,尤其是pH值和PCO2水平与ABG值具有较好的相关性。鉴于这种相关性并不紧密,在COPD急性加重期,VBG不能替代ABG。

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