Tavakol Kamran, Ghahramanpoori Bahareh, Fararouei Mohammad
Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Anesthesiology, School of Medicine, Islamic Azad University, Najafabad Branch, Najafabad, Iran.
J Med Signals Sens. 2013 Jul;3(3):180-4.
Substitution of arterial with venous blood samples to estimate blood gas status is highly preferable due to practical and safety concerns. Numerous studies support the substitution of arterial by venous blood samples, reporting strong correlations between arterial and venous values. This study further investigated the predictive ability of venous blood samples for arterial Acid-Base Balance (pH) and pressure of carbon dioxide (pCO2). Participants were 51 post-brain surgery patients receiving mechanical ventilation, who had blood samples taken simultaneously from radial artery of the wrist and elbow vein. Results showed significant associations between arterial and venous pH and pCO2. However, the variation of regression residuals was not homogenous, and the regression line did not fit properly to the data, indicating that simple linear regression is sub-optimal for prediction of arterial pH and pCO2 by venous blood sample. Although highly significant correlations were found between arterial and venous blood pH and pCO2, the results did not support the reliability of prediction of arterial blood pH and pCO2 by venous blood samples across a range of concentrations.
出于实际和安全考虑，用静脉血样替代动脉血样来评估血气状态是非常可取的。大量研究支持用静脉血样替代动脉血样，报告称动脉值与静脉值之间存在很强的相关性。本研究进一步调查了静脉血样对动脉酸碱平衡（pH值）和二氧化碳分压（pCO2）的预测能力。研究对象为51例接受机械通气的脑外科手术后患者，他们同时从手腕桡动脉和肘部静脉采集血样。结果显示动脉血与静脉血的pH值和pCO2之间存在显著关联。然而，回归残差的变化并不均匀，回归线与数据拟合不佳，这表明简单线性回归对于用静脉血样预测动脉血pH值和pCO2并非最优方法。尽管动脉血与静脉血的pH值和pCO2之间存在高度显著的相关性，但结果并不支持在一系列浓度范围内用静脉血样预测动脉血pH值和pCO2的可靠性。
