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RevoLix前列腺汽化切除术:54例患者1年随访的初步结果

RevoLix vaporesection of the prostate: initial results of 54 patients with a 1-year follow-up.

作者信息

Bach Thorsten, Herrmann Thomas R W, Ganzer Roman, Burchardt Martin, Gross Andreas J

机构信息

Department of Urology, Asklepios Hospital Barmbek, Ruebenkamp 220, 22291, Hamburg, Germany.

出版信息

World J Urol. 2007 Jun;25(3):257-62. doi: 10.1007/s00345-007-0171-x. Epub 2007 May 25.

Abstract

Multiple laser systems for the treatment of benign prostatic hyperplasia (BPH) have been introduced. Current laser systems have limitations due to their laser physics. The RevoLix laser combines the advantages of the Holmium:YAG laser with the comfort of a continuous wave (cw) laser beam. This study reports the preliminary results of vaporesection (simultaneous vaporization and resection) of the prostate, using the 2 microm cw laser. A total of 54 consecutive patients were treated with the 70 W RevoLix laser for BPH. The mean age was 61 years. Mean prostate volume was 30.3 cc. A 550 microm RigiFib bare-ended fiber was used in combination with a 26 French laser resectoscope. Measured outcomes were resection time, decrease in hemoglobin and transfusion rate. Furthermore, the catheter time, improvement in the urinary flow rate (Q(max)), post-voiding residual urine (PVR), International Prostate Symptom Score (IPSS) and Quality of Life Index (QoL) were recorded. Average resection time was 52 min. After crossing the learning curve, a tissue ablation of 1.5 g/min was possible. Transfusions were not necessary in any patient. Catheter time was 1.7 days. Q(max) significantly improved from 4.2 to 20.1 ml on average. PVR decreased from 86 to 12 ml. IPSS and QoL-Score improved from 19.8 to 6.9 and 4 to 1, respectively. No patient required re-hospitalization. These preliminary results indicate that RevoLix vaporesection of the prostate is safe and efficient. One-year follow-up data showed a significant improvement in voiding symptoms and patients' quality of life. A longer follow-up is needed to prove the durability of these promising results.

摘要

用于治疗良性前列腺增生(BPH)的多种激光系统已被引入。当前的激光系统由于其激光物理特性存在局限性。RevoLix激光结合了钬:钇铝石榴石激光的优点以及连续波(cw)激光束的舒适性。本研究报告了使用2微米连续波激光进行前列腺汽化切除(同时汽化和切除)的初步结果。共有54例连续患者接受了70W的RevoLix激光治疗BPH。平均年龄为61岁。平均前列腺体积为30.3立方厘米。使用一根550微米的RigiFib裸端光纤与一台26法式激光切除镜联合使用。测量的结果指标为切除时间、血红蛋白下降情况和输血率。此外,还记录了导尿管留置时间、尿流率(Q(max))改善情况、排尿后残余尿量(PVR)、国际前列腺症状评分(IPSS)和生活质量指数(QoL)。平均切除时间为52分钟。越过学习曲线后,组织消融速度可达1.5克/分钟。所有患者均无需输血。导尿管留置时间为1.7天。Q(max)平均从4.2显著提高至20.1毫升。PVR从86毫升降至12毫升。IPSS和QoL评分分别从19.8改善至6.9和从4改善至1。无患者需要再次住院。这些初步结果表明,RevoLix前列腺汽化切除是安全且有效的。一年的随访数据显示排尿症状和患者生活质量有显著改善。需要更长时间的随访来证实这些令人鼓舞的结果的持久性。

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