Arbel Yaron, Eros Yoav, Rogowski Ori, Berliner Shlomo, Shapira Itzhak, Keren Gad, Vered Yafa, Banai Shmuel
Interventional Cardiology, Department of Cardiology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Am J Cardiol. 2007 Jun 1;99(11):1504-6. doi: 10.1016/j.amjcard.2007.01.020. Epub 2007 Apr 16.
This study compared the recently introduced cheaper and more accessible wide-range C-reactive protein (wr-CRP) with the commonly used high-sensitivity C-reactive protein (hs-CRP) in patients undergoing coronary angiography. One hundred fifty-two consecutive patients who were admitted to a tertiary medical center and underwent angiography were included in the study. Arterial blood was obtained for the 2 assays at the beginning of angiography. A highly significant correlation (r = 0.983, p <0.001) was found between the 2 methods. This correlation was observed in different clinical scenarios and in different ranges of CRP. In conclusion, the real-time, online, and low-cost wr-CRP assay is a reasonable alternative to the Behring Dade hs-CRP method in the setting of stable and unstable coronary artery disease.
本研究在接受冠状动脉造影的患者中,将最近推出的更便宜且更容易获得的宽范围C反应蛋白(wr-CRP)与常用的高敏C反应蛋白(hs-CRP)进行了比较。该研究纳入了152例连续入住三级医疗中心并接受血管造影的患者。在血管造影开始时采集动脉血进行这两种检测。两种方法之间发现高度显著的相关性(r = 0.983,p <0.001)。在不同的临床情况和不同的CRP范围内均观察到这种相关性。总之,在稳定和不稳定冠状动脉疾病的情况下,实时、在线且低成本的wr-CRP检测是拜耳诊断hs-CRP方法的合理替代方法。