法国的普马拉病毒和图拉汉坦病毒。

Puumala and Tula hantaviruses in France.

作者信息

Plyusnina Angelina, Deter Julie, Charbonnel Nathalie, Cosson Jean-François, Plyusnin Alexander

机构信息

Department of Virology, Haartman Institute, University of Helsinki, P.O. Box 21 (Haartmaninkatu 3), FI-00014 Helsinki, Finland.

出版信息

Virus Res. 2007 Oct;129(1):58-63. doi: 10.1016/j.virusres.2007.04.023. Epub 2007 May 25.

DOI:10.1016/j.virusres.2007.04.023

PMID:17532080

Abstract

The first genome sequences of Tula (TULV) and Puumala (PUUV) hantaviruses undoubtedly originated from France were recovered from tissue samples of European common voles and bank voles captured in Jura region. Genetic analysis of S and M segments of French PUUV strain revealed its highest similarity to strains from neighboring Belgium and Germany and also from Slovakia. On phylogenetic trees, French PUUV strain was placed within the central European lineage formed by strains from these three countries. Both of our French TULV strains clustered together and formed a distinct, well-supported genetic lineage.

摘要

图拉汉坦病毒（TULV）和普马拉汉坦病毒（PUUV）最早源自法国的基因组序列，是从汝拉地区捕获的欧洲普通田鼠和棕背䶄的组织样本中获得的。对法国普马拉汉坦病毒株的S和M片段进行的基因分析表明，它与邻国比利时、德国以及斯洛伐克的毒株相似度最高。在系统发育树上，法国普马拉汉坦病毒株位于由这三个国家的毒株形成的中欧谱系内。我们的两个法国图拉汉坦病毒株聚集在一起，形成了一个独特的、得到充分支持的基因谱系。