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987例心血管手术后声带麻痹的发生率及危险因素

Incidence and risk factors of postoperative vocal cord paralysis in 987 patients after cardiovascular surgery.

作者信息

Itagaki Taiga, Kikura Mutsuhito, Sato Shigehito

机构信息

Department of Anesthesiology, Hamamatsu Medical Center, Hamamatsu, Japan.

出版信息

Ann Thorac Surg. 2007 Jun;83(6):2147-52. doi: 10.1016/j.athoracsur.2007.02.008.

Abstract

BACKGROUND

Vocal cord paralysis (VCP) after cardiovascular surgery can affect the postoperative outcome. The aim of the present study was to clarify the incidence of VCP after cardiovascular surgery and the relationship between the surgery characteristics and the risk of VCP.

METHODS

A total of 987 consecutive patients who underwent cardiovascular surgery (cardiac, n = 895; aortic, n = 92) were enrolled. We retrospectively assessed the incidence and the risk of VCP according to the length and types of surgery and the details of each VCP case and compared them between the aortic and the nonaortic group.

RESULTS

Twenty-three patients (2.3%: cardiac, n =15; aortic, n = 8) were expertly diagnosed with VCP (left, n = 19; right, n = 2; bilateral, n = 2). In the multivariate analysis, the risk for VCP increased with the duration of the operation (odds ratio [OR], 4.4, 95% confidence interval [CI] 1.7 to 11.4), and aortic procedures (OR, 5.6, CI 2.3 to 13.5) exhibited higher risk compared with coronary artery bypass grafting. Among the VCP cases, the incidence of poor outcomes (ie, bilateral VCP, repeated airway treatment, death within 6 months) was significantly higher in the aortic group (p = 0.016). All patients that were intubated for longer than 100 hours exhibited poor outcomes.

CONCLUSIONS

Aortic procedures and prolonged operation increase the risk of VCP. Severe VCP tended to be associated with aortic surgery and intubation for more than 100 hours.

摘要

背景

心血管手术后声带麻痹(VCP)会影响术后结果。本研究的目的是明确心血管手术后VCP的发生率以及手术特征与VCP风险之间的关系。

方法

共纳入987例连续接受心血管手术的患者(心脏手术,n = 895;主动脉手术,n = 92)。我们根据手术时长、类型以及每例VCP病例的详细情况,回顾性评估VCP的发生率和风险,并在主动脉手术组和非主动脉手术组之间进行比较。

结果

23例患者(2.3%:心脏手术患者15例,主动脉手术患者8例)被确诊为VCP(左侧19例,右侧2例,双侧2例)。多因素分析显示,VCP风险随手术时间延长而增加(优势比[OR]为4.4,95%置信区间[CI]为1.7至11.4),与冠状动脉旁路移植术相比,主动脉手术(OR为5.6,CI为2.3至13.5)的风险更高。在VCP病例中,主动脉手术组不良结局(即双侧VCP、反复气道治疗、6个月内死亡)的发生率显著更高(p = 0.016)。所有气管插管超过100小时的患者均出现不良结局。

结论

主动脉手术和手术时间延长会增加VCP风险。严重VCP往往与主动脉手术以及气管插管超过100小时有关。

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