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胸主动脉手术后声带麻痹:发生率及其对临床结局的影响

Vocal Cord Paralysis After Thoracic Aortic Surgery: Incidence and Impact on Clinical Outcomes.

作者信息

Lodewyks Carly L, White Christopher W, Bay Graham, Hiebert Brett, Wu Bella, Barker Mark, Kirkpatrick Iain, Arora Rakesh C, Moon Michael, Pascoe Edward

机构信息

Department of Surgery, Section of Cardiac Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.

Department of Radiology, University of Manitoba, Winnipeg, Manitoba, Canada.

出版信息

Ann Thorac Surg. 2015 Jul;100(1):54-8. doi: 10.1016/j.athoracsur.2015.02.021. Epub 2015 Apr 15.

Abstract

BACKGROUND

Vocal cord paralysis (VCP) is a serious complication associated with thoracic aortic surgery; however, there is a paucity of literature regarding the incidence and impact of VCP on postoperative outcomes. We sought to determine the incidence of VCP and its impact on clinical outcomes in patients who underwent thoracic aortic repair at our center.

METHODS

A retrospective chart review was conducted on all patients who underwent thoracic aortic surgery between January 2009 and September 2012.

RESULTS

A total of 259 patients underwent a thoracic aortic procedure during the study period. Vocal cord paralysis was diagnosed in 12 (5%) patients, a median of 6 [3 to 21] days after extubation. The incidence was 1%, 0%, 20%, and 25% in those undergoing an open ascending, hemiarch, total arch, or descending aortic procedure, respectively. Patients with VCP had an increased incidence of pneumonia (58% vs 17%, p = 0.003), readmission to the intensive care unit for respiratory failure (17% vs 2%, p = 0.047), and longer hospital length of stay (18 [11 to 43] days versus 9 [6 to 15] days, p = 0.002). A propensity-matched analysis confirmed a higher incidence of pneumonia (58% vs 17%, p = 0.020) and longer hospital length of stay (18 [11 to 43] vs 10 [7 to 14] days, p = 0.015) in patients suffering VCP.

CONCLUSIONS

Vocal cord paralysis is a common complication in patients undergoing open surgery of the aortic arch and descending aorta, and is associated with significant morbidity. Further research may be warranted to determine if early fiberoptic examination and consideration of a vocal cord medialization procedure may mitigate the morbidity associated with VCP.

摘要

背景

声带麻痹(VCP)是胸主动脉手术的一种严重并发症;然而,关于VCP的发生率及其对术后结局影响的文献较少。我们试图确定在我们中心接受胸主动脉修复的患者中VCP的发生率及其对临床结局的影响。

方法

对2009年1月至2012年9月期间接受胸主动脉手术的所有患者进行回顾性病历审查。

结果

在研究期间,共有259例患者接受了胸主动脉手术。12例(5%)患者被诊断为声带麻痹,拔管后中位时间为6[3至21]天。在接受升主动脉开放手术、半弓手术、全弓手术或降主动脉手术的患者中,发生率分别为1%、0%、20%和25%。VCP患者肺炎发生率增加(58%对17%,p = 0.003),因呼吸衰竭再次入住重症监护病房的发生率增加(17%对2%,p = 0.047),住院时间延长(18[11至43]天对9[6至15]天,p = 0.002)。倾向匹配分析证实,VCP患者肺炎发生率更高(58%对17%,p = 0.020),住院时间更长(18[11至43]天对10[7至14]天,p = 0.015)。

结论

声带麻痹是接受主动脉弓和降主动脉开放手术患者的常见并发症,且与显著的发病率相关。可能需要进一步研究以确定早期纤维喉镜检查和考虑声带内移手术是否可减轻与VCP相关的发病率。

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