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[恶性肿瘤患儿中抗爱泼斯坦-巴尔病毒衣壳抗原的抗体(作者译)]

[Antibodies against the Epstein-Barr virus, capsid antigen in children with malignant neoplasms (author's transl)].

作者信息

Lubec G, Krepler P

出版信息

Padiatr Padol. 1976;11(1):88-93.

PMID:175342
Abstract

Sera from children were tested for antibodies to viral capsid antigens of Epstein-Barr virus. The method applied was the indirect immunofluorescence test. 25 sera from healthy donors were titrated as controls. In 14 patients with acute lymphocytic leukemia we found low levels, a tiny little girl with chronic myelocytic leukemia (?) AND THREE CHILDREN.WITH LYMPHOPROLIFERATIVE DISORDERS SHOWed highly increased serological reactivities. Investigated children with other kinds of tumours did not serologically differ significantly from the control group. Further investigations should clarify the role of this infectious agent.

摘要

检测儿童血清中针对EB病毒病毒衣壳抗原的抗体。采用的方法是间接免疫荧光试验。将25份来自健康供者的血清作为对照进行滴定。在14例急性淋巴细胞白血病患者中我们发现抗体水平较低,一名患有慢性粒细胞白血病(?)的小女孩以及三名患有淋巴增殖性疾病的儿童血清学反应性显著升高。患有其他类型肿瘤的受试儿童在血清学上与对照组无显著差异。进一步的研究应阐明这种感染因子的作用。

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