Frisch I B, Rabsilber T M, Becker K A, Reuland A J, Auffarth G U
Department of Ophthalmology, Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany.
Eur J Ophthalmol. 2007 May-Jun;17(3):327-31. doi: 10.1177/112067210701700308.
To evaluate and compare anterior chamber depth (ACD) measurements using Orbscan II (Bausch & Lomb, Rochester, NY) and IOLMaster (Carl Zeiss Meditec AG, Jena, Germany).
In this prospective clinical study, the authors measured ACD of 145 phakic eyes of 30 healthy volunteers and 115 patients using Orbscan II and IOLMaster. Average patient age was 52.9+/-19.4 (range 16 to 87) years. ACD was evaluated from corneal epithelium to anterior lens surface. Additionally, axial length (AL) was measured using the Zeiss IOLMaster to calculate the regression coefficient between AL and ACD.
Mean ACD was 3.35+/-0.43 mm (range 2.01 mm to 4.37 mm) using Orbscan II and 3.36+/-0.41 mm (range 2.09 mm to 4.24 mm) using IOLMaster. Mean total axial length was 24.04 mm +/- 2.1 mm (range 20.7 mm to 31.41 mm). The linear regression coefficient of ACD between both methods was R=0.95. ACD and AL correlated only slightly (R=0.57). The Spearman coefficients of rank correlation were 0.94 and 0.61, respectively. A p value less than 0.01 (paired Wilcoxon test) was considered statistically significant. However, a significant difference was not calculated comparing ACD measurements using both systems and the Bland-Altman-Plot showed 95% of the differences ranging between 0.25 and -0.27 mm.
Regarding clinical application, both systems seem to be equally good and interchangeable in clinical practice in terms of ACD evaluation.
评估并比较使用Orbscan II（博士伦公司，纽约州罗切斯特）和IOLMaster（卡尔·蔡司医疗技术股份公司，德国耶拿）测量前房深度（ACD）的情况。
在这项前瞻性临床研究中，作者使用Orbscan II和IOLMaster测量了30名健康志愿者和115名患者的145只晶状体眼的ACD。患者平均年龄为52.9±19.4（范围16至87）岁。从角膜上皮至晶状体前表面评估ACD。此外，使用蔡司IOLMaster测量眼轴长度（AL），以计算AL与ACD之间的回归系数。
使用Orbscan II测量的平均ACD为3.35±0.43毫米（范围2.01毫米至4.37毫米），使用IOLMaster测量的平均ACD为3.36±0.41毫米（范围2.09毫米至4.24毫米）。平均总眼轴长度为24.04毫米±2.1毫米（范围20.7毫米至31.41毫米）。两种方法之间ACD的线性回归系数为R = 0.95。ACD与AL仅存在轻微相关性（R = 0.57）。Spearman等级相关系数分别为0.94和0.61。p值小于0.01（配对Wilcoxon检验）被认为具有统计学意义。然而，比较两种系统测量的ACD时未计算出显著差异，Bland-Altman图显示95%的差异在0.25至 -0.27毫米之间。
就临床应用而言，在ACD评估方面，两种系统在临床实践中似乎同样出色且可相互替代。
