Dong Jing, Tang Maolong, Zhang Yaqin, Jia Yading, Zhang Haining, Jia Zhijie, Wang Xiaogang
The First Hospital of Shanxi Medical University, Shanxi, P.R. China.
Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America.
PLoS One. 2015 Nov 17;10(11):e0143110. doi: 10.1371/journal.pone.0143110. eCollection 2015.
To compare the anterior chamber depth (ACD), keratometry (K) and astigmatism measurements taken by IOLMaster and Pentacam HR in normal and high myopic (HM) eyes.
A prospective observational case series.
Sixty-six normal eyes and 59 HM eyes underwent ACD, keratometry and astigmatism measurements with both devices. Axial length (AL) was measured on IOLMaster. The interdevice agreement was evaluated using the Bland-Altman analysis and paired t-test. The correlations between age and AL & ACD were analyzed. Vector analysis was used to compare astigmatism measurements.
The ACD from IOLMaster and Pentacam HR was different for the normal group (P = 0.003) but not for the HM group (P = 0.280). IOLMaster demonstrated higher steep K and mean K values than Pentacam HR for both normal and HM groups (P<0.001 for all). IOLMaster also have higher flat K values for the HM groups (P<0.001) but were statistically equivalent with Pentacam HR for the normal group (P = 0.119) IOLMaster and Pentacam HR were different in astigmatism measurements for the normal group but were statistically equivalent for the HM group. For the normal group, age was negatively correlated with AL, IOLMaster ACD and Pentacam HR ACD (r = -0.395, P = 0.001; r = -0.715, P < 0.001; r = -0.643, P < 0.001). For the HM group, age was positively correlated with AL but negatively correlated with IOLMaster ACD and Pentacam HR ACD (r = 0.377, P = 0.003; r = -0.392, P = 0.002; r = -0.616, P < 0.001).
The IOLMaster and Pentacam HR have significant difference in corneal power measurements for both normal and HM groups. The two instruments also differ in ACD and astigmatism measurement for the normal group. Therefore, a single instrument is recommended for studying longitudinal changes in anterior segment biometric measurements. Age should be considered as an influencing factor for both AL and ACD values in the normal and HM group.
比较IOLMaster和Pentacam HR在正常眼和高度近视眼（HM）中测量的前房深度（ACD）、角膜曲率（K）和散光。
前瞻性观察病例系列。
66只正常眼和59只HM眼使用这两种设备进行ACD、角膜曲率和散光测量。在IOLMaster上测量眼轴长度（AL）。使用Bland-Altman分析和配对t检验评估设备间的一致性。分析年龄与AL和ACD之间的相关性。使用矢量分析比较散光测量结果。
正常组中IOLMaster和Pentacam HR测量的ACD不同（P = 0.003），但HM组中无差异（P = 0.280）。对于正常组和HM组，IOLMaster显示的陡峭K值和平均K值均高于Pentacam HR（所有P<0.001）。HM组中IOLMaster的扁平K值也更高（P<0.001），但正常组中与Pentacam HR在统计学上相当（P = 0.119）。IOLMaster和Pentacam HR在正常组的散光测量中不同，但在HM组中在统计学上相当。对于正常组，年龄与AL、IOLMaster ACD和Pentacam HR ACD呈负相关（r = -0.395，P = 0.001；r = -0.715，P <0.001；r = -0.643，P <0.001）。对于HM组，年龄与AL呈正相关，但与IOLMaster ACD和Pentacam HR ACD呈负相关（r = 0.377，P = 0.003；r = -0.392, P = 0.002；r = -0.616，P <0.001）。
IOLMaster和Pentacam HR在正常组和HM组的角膜屈光力测量中存在显著差异。这两种仪器在正常组的ACD和散光测量中也存在差异。因此，建议使用单一仪器研究眼前节生物测量的纵向变化。在正常组和HM组中，年龄应被视为影响AL和ACD值的一个因素。
