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使用新型非接触式光学低相干反射仪进行眼生物测量的比较与评估

Comparison and evaluation of ocular biometry using a new noncontact optical low-coherence reflectometer.

作者信息

Rohrer Kaspar, Frueh Beatrice E, Wälti Rudolf, Clemetson Isabelle A, Tappeiner Christoph, Goldblum David

机构信息

Department of Ophthalmology, Inselspital, University Bern, Bern, Switzerland.

出版信息

Ophthalmology. 2009 Nov;116(11):2087-92. doi: 10.1016/j.ophtha.2009.04.019. Epub 2009 Sep 10.

Abstract

PURPOSE

To evaluate a new high-resolution noncontact biometer (Lenstar; Haag-Streit AG, Koeniz, Switzerland) using optical low-coherence reflectometry and to compare the clinical measurements with those obtained from the IOLMaster (Carl Zeiss, Jena, Germany) and the Pachmumeter (Haag-Streit AG).

DESIGN

Exploratory evaluation of diagnostic technology and nonrandomized, prospective clinical trial.

PARTICIPANTS

Eighty subjects (144 eyes) aged 20 to 90 years with cataractous, pseudophakic, aphakic, silicon oil-filled, or normal eyes.

METHODS

Measurements of axial length (AL), anterior chamber depth (ACD), central corneal thickness (CCT), corneal radius (R1 [flattest radius of corneal curvature] and R2 [steep radius, 90 degrees apart from R1]), and axis of the flattest radius (Ax1) obtained with the Lenstar were compared with those obtained with the IOLMaster or Pachmumeter. The results were evaluated using Bland-Altman analyses. The differences between both methods were assessed using the paired t test, and its correlation was evaluated by Pearson coefficient.

MAIN OUTCOME MEASURES

Axial length, CCT, ACD, R1, R2, and Ax1.

RESULTS

The overall mean AL measured with the Lenstar and the IOLMaster was 24.1 mm (r = 0.999). Anterior chamber depth was 3.19 mm (Lenstar) and 3.17 mm (IOLMaster; r = 0.875). Excellent correlations also were found for the corneal radius and the axis of flattest radius (R1, r = 0.927; R2, r = 0.929; and Ax1, r = 0.938). Mean CCT was 0.557 mm (r = 0.978) for both Lenstar and Pachmumeter.

CONCLUSIONS

Measurements with the new Lenstar correlated well with those with the IOLMaster and Pachmumeter in cataractous, pseudophakic, aphakic, silicon oil-filled, and normal eyes. It is an accurate, fast instrument that provides additional information of interest to any cataract or refractive surgeon.

摘要

目的

使用光学低相干反射测量法评估一种新型高分辨率非接触式生物测量仪(Lenstar;瑞士科尼茨哈格-施特赖特公司),并将临床测量结果与使用IOLMaster(德国耶拿卡尔蔡司公司)和角膜厚度测量仪(哈格-施特赖特公司)获得的结果进行比较。

设计

诊断技术的探索性评估及非随机前瞻性临床试验。

研究对象

80名年龄在20至90岁之间,患有白内障、人工晶状体眼、无晶状体眼、硅油填充眼或正常眼的受试者(144只眼)。

方法

将使用Lenstar获得的眼轴长度(AL)、前房深度(ACD)、中央角膜厚度(CCT)、角膜半径(R1[角膜曲率最平半径]和R2[陡峭半径,与R1相隔90度])以及最平半径的轴(Ax1)测量结果与使用IOLMaster或角膜厚度测量仪获得的结果进行比较。使用Bland-Altman分析评估结果。使用配对t检验评估两种方法之间的差异,并通过Pearson系数评估其相关性。

主要观察指标

眼轴长度、CCT、ACD、R1、R2和Ax1。

结果

使用Lenstar和IOLMaster测量的总体平均眼轴长度为24.1mm(r = 0.999)。前房深度分别为3.19mm(Lenstar)和3.17mm(IOLMaster;r = 0.875)。在角膜半径和最平半径的轴方面也发现了极好的相关性(R1,r = 0.927;R2,r = 0.929;Ax1,r = 0.938)。Lenstar和角膜厚度测量仪测量的平均CCT均为0.557mm(r = 0.978)。

结论

在白内障、人工晶状体眼、无晶状体眼、硅油填充眼和正常眼中,新型Lenstar的测量结果与IOLMaster和角膜厚度测量仪的测量结果相关性良好。它是一种准确、快速的仪器,可为任何白内障或屈光手术医生提供有价值的额外信息。

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