Marshall Nathaniel S, Almqvist Catarina, Grunstein Ronald R, Marks Guy B
Woolcock Institute of Medical Research, Sydney, NSW, Australia.
Pediatr Pulmonol. 2007 Jul;42(7):584-91. doi: 10.1002/ppul.20606.
Snoring is often found in allergic diseases and may be an early manifestation of more serious sleep-disordered breathing. We aimed to investigate whether the risk factors for snoring among pre-school children with rhinitis are similar to those for allergic diseases in a birth cohort. The study cohort was drawn from participants in the Childhood Asthma Prevention Study (CAPS). This is a randomized controlled trial of dietary intervention and house dust mite avoidance during the first 5 years of life, aimed at reducing the risk of acquiring asthma and other allergic conditions in children at high-risk for allergic diseases. Parents of children with symptoms of rhinitis at age 5 years (n = 219 out of 516 cohort members) were asked if their child snored: 127 (60%) reported some snoring and 56 (26%) snored more than three times per week. Multiple logistic regression analyses indicated that children who were first-born (adjusted odds ratio, 2.50, 95% CI 1.20-5.21), were exposed to maternal tobacco smoke during the first year of life (2.40, 1.1-5.25), or who had asthma (2.51, 1.14-5.55) and/or eczema (2.29, 1.02-5.13) at age 5 years were more likely to snore. Birth-weight, body mass index at age 4.5, spirometry, and breastfeeding were not related to snoring. Risk factors for snoring are similar to risk factors for allergic disorders. Snoring may be part of the allergic spectrum of diseases. Our data may contribute to clinician's ability to effectively screen for snoring in preschool children.
打鼾在过敏性疾病中很常见,可能是更严重的睡眠呼吸障碍的早期表现。我们旨在调查鼻炎学龄前儿童打鼾的危险因素是否与出生队列中过敏性疾病的危险因素相似。研究队列来自儿童哮喘预防研究(CAPS)的参与者。这是一项针对生命最初5年进行饮食干预和避免接触屋尘螨的随机对照试验,旨在降低过敏性疾病高危儿童患哮喘和其他过敏性疾病的风险。询问了5岁时有鼻炎症状的儿童(516名队列成员中的219名)的父母其孩子是否打鼾:127名(60%)报告有一些打鼾,56名(26%)每周打鼾超过三次。多因素logistic回归分析表明,头胎出生的儿童(调整后的优势比,2.50,95%可信区间1.20 - 5.21)、在生命的第一年接触过母亲吸烟的儿童(2.40,1.1 - 5.25),或5岁时患有哮喘(2.51,1.14 - 5.55)和/或湿疹(2.29,1.02 - 5.13)的儿童更有可能打鼾。出生体重、4.5岁时的体重指数、肺功能测定和母乳喂养与打鼾无关。打鼾的危险因素与过敏性疾病的危险因素相似。打鼾可能是过敏性疾病谱的一部分。我们的数据可能有助于临床医生有效筛查学龄前儿童的打鼾情况。