Koyama Y, Ako H, Katada H, Hamada K, Kasuga H, Nishikawa K, Narita N, Iioka S, Kitamura S, Kitagawa M
Second Department of Internal Medicine, Nara Medical University.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Aug;29(8):1052-8.
A 65-year-old man was admitted to our hospital complaining of productive cough, dyspnea and stridor. Chest X-ray disclosed overinflation with micronodular infiltrates. Blood examination showed mild eosinophilia and IgE elevation. Pulmonary function test disclosed severe airway obstruction and diffusion capacity impairment. Although clinical improvement was achieved after bronchodilator therapy, laboratory abnormalities continued. Open lung biopsy demonstrated mononuclear cellular and eosinophilic infiltration at alveolar lumen and vessel walls without prominent fibrosis, which was compatible for prolonged eosinophilic pneumonia. From above findings, this case was thought as a prolonged eosinophilic pneumonia combined with pulmonary emphysema and bronchial asthma.
一名65岁男性因咳嗽、咳痰、呼吸困难和喘鸣入住我院。胸部X线显示过度充气伴微小结节浸润。血液检查显示轻度嗜酸性粒细胞增多和IgE升高。肺功能测试显示严重气道阻塞和弥散功能障碍。尽管支气管扩张剂治疗后临床症状有所改善，但实验室异常仍持续存在。开胸肺活检显示肺泡腔和血管壁有单核细胞和嗜酸性粒细胞浸润，无明显纤维化，符合迁延性嗜酸性粒细胞性肺炎。根据上述发现，该病例被认为是迁延性嗜酸性粒细胞性肺炎合并肺气肿和支气管哮喘。
