Kim Y C, Taniguchi T, Kawarazaki S, Takasu K
Department of Clinical Laboratory Medicine, Kyoto City Hospital, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 Aug;29(8):1083-7.
The classical from of Wegener's granulomatosis (WG) is a necrotizing granulomatous angiitis that involves the upper and lower airways, and kidneys. A limited form of WG is characterized by pulmonary lesions identical to those of classical form WG without renal involvement. The authors report a case of limited form WG. A 58-year-old Japanese woman was admitted because of an abnormal pulmonary shadow. Pathological examination revealed granulomatous angiitis consistent with WG. No other organ involvement was found. The pulmonary shadow improved with cyclophosphamide therapy. The patient is now well and without evidence of exacerbation of the disease 18 month after the discharge.
韦格纳肉芽肿（WG）的典型形式是一种坏死性肉芽肿性血管炎，累及上、下呼吸道及肾脏。局限性韦格纳肉芽肿的特征是肺部病变与典型韦格纳肉芽肿相同，但无肾脏受累。作者报告了一例局限性韦格纳肉芽肿病例。一名58岁日本女性因肺部阴影异常入院。病理检查显示符合韦格纳肉芽肿的肉芽肿性血管炎。未发现其他器官受累。环磷酰胺治疗后肺部阴影改善。患者现已康复，出院18个月后无疾病复发迹象。
