职业噪声暴露对外周血去甲肾上腺素及心血管系统的影响
[Effects of occupational noise exposure on norepinephrine in peripheral blood and cardiovascular system].
作者信息
Liu Yi-min, Lai Jian-min, Xiao Qi-hua, Xiao Lv-wu, Yang Zhen-yu, Luo Xiao-li
机构信息
Guangzhou Prevention and Treatment Center for Occupational Disease, Guangzhou 510620, China.
出版信息
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007 Apr;25(4):227-9.
OBJECTIVE
To study the effects of noise on bioactivity of norepinephrine (NE) and cardiovascular system.
METHODS
A total of 130 workers exposed to the occupational noise in one enterprise were selected as noise exposure group, and 134 workers not exposed to the occupational noise and other poisons served as control group. Fasting venous blood was drawn to determine the content of NE in peripheral blood with ELISA. According to Occupational Health Surveillance Manage regulations, the occupational noise exposures crowd was examined.
RESULTS
The average of NE in exposure group was (0.1387 +/- 0.099) ng/ml, and (0.1019 +/- 0.080) ng/ml in control group. There was significant difference in NE between exposure and control group. There was significant difference in the detection rate of BP, HR and ECG between exposure and control group.
CONCLUSION
The occupation noise can increase the NE in peripheral blood, and maybe affects the cardiovascular system in this way.
目的
研究噪声对去甲肾上腺素（NE）生物活性及心血管系统的影响。
方法
选取某企业130名接触职业噪声的工人作为噪声暴露组，134名未接触职业噪声及其他毒物的工人作为对照组。抽取空腹静脉血，采用酶联免疫吸附测定法（ELISA）测定外周血NE含量。按照《职业健康监护管理办法》对职业噪声暴露人群进行检查。
结果
暴露组NE平均值为（0.1387±0.099）ng/ml，对照组为（0.1019±0.080）ng/ml。暴露组与对照组NE差异有统计学意义。暴露组与对照组血压、心率及心电图检出率差异有统计学意义。
结论
职业噪声可使外周血NE升高，可能由此影响心血管系统。
Zotero 插件