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垂体手术后早期低钠血症:脑性盐耗综合征。

Early hyponatraemia after pituitary surgery: cerebral salt-wasting syndrome.

作者信息

Guerrero R, Pumar A, Soto A, Pomares M A, Palma S, Mangas M A, Leal A, Villamil F

机构信息

Department of Endocrinology and Nutrition, Hospital Universitario Virgen del Rocío, Avenida Manuel Siurot S/N, 41013 Seville, Spain.

出版信息

Eur J Endocrinol. 2007 Jun;156(6):611-6. doi: 10.1530/EJE-06-0659.

DOI:10.1530/EJE-06-0659
PMID:17535859
Abstract

Hyponatraemia is a common complication in patients undergoing neurosurgery. It can be caused either by the syndrome of inappropriate secretion of antidiuretic hormone or by the cerebral salt-wasting syndrome (CSWS). CSWS frequently occurs in patients suffering from subarachnoid haemorrhage and brain injury, but it is rare after pituitary tumour surgery. However, this diagnostic possibility should be considered as these disorders require specific treatment and have different prognoses. In this article, we present a case of acute and early hyponatraemia caused by CSWS after pituitary tumour surgery. We also revise the aetiology, mechanisms, differential diagnosis and treatment of hyponatraemia after pituitary surgery.

摘要

低钠血症是神经外科手术患者常见的并发症。它可能由抗利尿激素分泌不当综合征或脑性盐耗综合征(CSWS)引起。CSWS常见于蛛网膜下腔出血和脑损伤患者,但垂体肿瘤手术后罕见。然而,由于这些疾病需要特殊治疗且预后不同,应考虑这种诊断可能性。在本文中,我们报告了一例垂体肿瘤手术后由CSWS引起的急性早期低钠血症病例。我们还对垂体手术后低钠血症的病因、机制、鉴别诊断和治疗进行了综述。

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