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可吸食的(“冰毒”、“甲基苯丙胺晶体”)和不可吸食的苯丙胺类兴奋剂:临床药理学和流行病学问题,特别提及英国

Smokable ("ice", "crystal meth") and non smokable amphetamine-type stimulants: clinical pharmacological and epidemiological issues, with special reference to the UK.

作者信息

Schifano Fabrizio, Corkery John M, Cuffolo Giulio

机构信息

School of Pharmacy University of Hertfordshire, College Lane Campus, Hatfield, Herts AL10 9AB (UK).

出版信息

Ann Ist Super Sanita. 2007;43(1):110-5.

PMID:17536161
Abstract

"Ice", "crystal meth", is the smokable form of methamphetamine hydrochloride. This paper will comment on the pharmacological, epidemiological, clinical and social issues related to smoking the drug as opposed to either its injection or ingestion. Furthermore, some data related to amphetamines/methamphetamines consumption, request for treatment, seizures, related offences and deaths in the UK (1990-2002) will be offered here. Peak rates, for most indicators, were reached at the end of the '90s, to fall down in the following years. The only indicator which seemed not to show any declining rates is number of deaths, but this may be related to a more general increase in stimulant death rates recently observed in the UK. It is argued that methamphetamines, and particularly "crystal meth", could reach the same prevalence levels of use in the UK as it is already in the US but recent reclassification of the drug to Class A in the UK could help to better control this emerging issue.

摘要

“冰毒”,即甲基苯丙胺盐酸盐的可吸食形式。本文将对吸食该毒品(与注射或口服相比)所涉及的药理学、流行病学、临床及社会问题进行评论。此外,还将提供一些与英国(1990 - 2002年)苯丙胺/甲基苯丙胺消费、治疗需求、缉获量、相关犯罪及死亡情况有关的数据。在90年代末,大多数指标达到峰值,随后几年有所下降。唯一似乎未显示出下降趋势的指标是死亡人数,但这可能与英国近期观察到的兴奋剂死亡率普遍上升有关。有人认为,甲基苯丙胺,尤其是“冰毒”,在英国的使用流行程度可能会达到美国现有的水平,但英国最近将该毒品重新归类为A类可能有助于更好地控制这一新兴问题。

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