Poniecka Anna, Ghorab Zeina, Arnold David, Khaled Amr, Ganjei-Azar Parvin
Department of Pathology, University of Miami, Holtz Center, Florida 33136, USA.
Acta Cytol. 2007 May-Jun;51(3):421-3. doi: 10.1159/000325758.
Kaposi's sarcoma (KS) is a neoplastic disease that affects primarily the skin, but visceral involvement is not uncommon. Most of the cases are seen in AIDS patients and transplant recipients; however, rare HIV-negative cases have also been reported. Involvement of the thyroid is exceedingly rare, with only a fw cases reported, all of them associated with AIDS.
A 45-year-old, black, Haitian woman presented with a slowly enlarging left side of the thyroid. Computed tomography showed multiple thyroid nodules, and there was no uptake of iodine on the nuclear scan. Fine needle aspiration of the lesion was performed. The smears were composed of spindle and plasmacytoid cells, which raised the possibility of medullary carcinoma. The patient underwent left hemithyroidectomy. Histologic examination showed KS in the thyroid.
We present the first case of KS of the thyroid in a HIV-negative patient. Familiarity with the cytologic features can be useful in making the diagnosis.
卡波西肉瘤（KS）是一种主要影响皮肤的肿瘤性疾病，但内脏受累并不罕见。大多数病例见于艾滋病患者和移植受者；然而，也有罕见的HIV阴性病例报道。甲状腺受累极为罕见，仅有少数病例报道，且均与艾滋病相关。
一名45岁的海地黑人女性，左侧甲状腺缓慢增大。计算机断层扫描显示多个甲状腺结节，核素扫描未摄取碘。对病变进行了细针穿刺抽吸。涂片由梭形细胞和浆细胞样细胞组成，提示髓样癌的可能性。患者接受了左侧甲状腺叶切除术。组织学检查显示甲状腺存在卡波西肉瘤。
我们报道了首例HIV阴性患者的甲状腺卡波西肉瘤病例。熟悉其细胞学特征有助于做出诊断。
