Hopf Harriet W, Rollins Mark D
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA.
Antioxid Redox Signal. 2007 Aug;9(8):1183-92. doi: 10.1089/ars.2007.1641.
We sought to review the role of oxygen in wound healing, with an emphasis on the role tissue oximetry has played in clinical advances in the care of patients with wounds. Oxygen is required for wound healing. Hypoxia sufficient to impair healing is common in wounds, frequently resulting from sympathetically induced vasoconstriction. Correction or prevention of vasoconstriction, as well as provision of increased inspired oxygen in well-perfused patients, has been shown in randomized, controlled clinical trials to improve wound outcomes. Our understanding of the role of oxygen in wound healing has been fueled by tissue oximetry. Advances in technology will lead to further advances in the management of patients with wounds.
我们试图回顾氧气在伤口愈合中的作用，重点关注组织血氧饱和度测定在伤口患者护理临床进展中所起的作用。伤口愈合需要氧气。足以损害愈合的缺氧在伤口中很常见，通常是由交感神经诱导的血管收缩所致。在随机对照临床试验中已表明，纠正或预防血管收缩，以及为灌注良好的患者提供增加的吸入氧气，可改善伤口预后。组织血氧饱和度测定推动了我们对氧气在伤口愈合中作用的理解。技术进步将导致伤口患者管理的进一步进展。
