无线和无电池技术在神经工程中的应用。
Wireless and battery-free technologies for neuroengineering.
机构信息
Department of Electrical and Computer Engineering, Sungkyunkwan University, Suwon, South Korea.
Biomedical Engineering, College of Engineering, The University of Arizona, Tucson, AZ, USA.
出版信息
Nat Biomed Eng. 2023 Apr;7(4):405-423. doi: 10.1038/s41551-021-00683-3. Epub 2021 Mar 8.
Abstract
Tethered and battery-powered devices that interface with neural tissues can restrict natural motions and prevent social interactions in animal models, thereby limiting the utility of these devices in behavioural neuroscience research. In this Review Article, we discuss recent progress in the development of miniaturized and ultralightweight devices as neuroengineering platforms that are wireless, battery-free and fully implantable, with capabilities that match or exceed those of wired or battery-powered alternatives. Such classes of advanced neural interfaces with optical, electrical or fluidic functionality can also combine recording and stimulation modalities for closed-loop applications in basic studies or in the practical treatment of abnormal physiological processes.
摘要
与神经组织接口的有绳和电池供电设备可能会限制动物模型中的自然运动并阻碍社交互动，从而限制了这些设备在行为神经科学研究中的应用。在这篇综述文章中，我们讨论了微型化和超轻设备作为神经工程平台的最新进展，这些设备无线、无电池且完全可植入，其功能与有线或电池供电的替代品相匹配或超过后者。这类具有光学、电学或流体功能的先进神经接口还可以结合记录和刺激模式，用于基础研究或实际治疗异常生理过程中的闭环应用。
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