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氧气作为新生儿健康危害:呼吁临床实践中缓和使用

Oxygen as a neonatal health hazard: call for détente in clinical practice.

作者信息

Sola Augusto, Rogido Marta R, Deulofeut Richard

机构信息

Mid Atlantic Neonatology Associates and Morristown Memorial Hospital, Morristown, NJ, USA.

出版信息

Acta Paediatr. 2007 Jun;96(6):801-12. doi: 10.1111/j.1651-2227.2007.00287.x.

Abstract

UNLABELLED

Education in oxygenation and in how oxygen is given to newborns needs to increase. Treatment with oxygen should no longer be considered proverbial and customary, regardless of our 'past experience' or consensus recommendations in clinical guidelines, since oxygen may lead to acute or chronic health effects.

CONCLUSION

Inappropriate oxygen use is a neonatal health hazard associated with aging, DNA damage and cancer, retinopathy of prematurity, injury to the developing brain, infection and others. Neonatal exposure to pure O2, even if brief, or to pulse oximetry >95% when breathing supplemental O2 must be avoided as much as possible.

摘要

未标注

关于新生儿氧合作用以及如何给新生儿输氧的教育需要加强。无论我们的“既往经验”或临床指南中的共识性建议如何,氧疗都不应再被视为理所当然和习以为常的做法,因为氧可能会导致急性或慢性健康影响。

结论

不恰当的氧使用是一种新生儿健康危害,与衰老、DNA损伤和癌症、早产儿视网膜病变、发育中的大脑损伤、感染及其他情况相关。必须尽可能避免新生儿暴露于纯氧(即使是短暂暴露),或在呼吸补充氧气时暴露于脉搏血氧饱和度>95%的情况。

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