McCord Shannon S, Naik-Mathuria Bindi J, Murphy Kathy M, McLane Kathy M, Gay Andre N, Bob Basu C, Downey Cara R, Hollier Larry H, Olutoye Oluyinka O
Texas Children's Hospital, Houston, Texas, USA.
Wound Repair Regen. 2007 May-Jun;15(3):296-301. doi: 10.1111/j.1524-475X.2007.00229.x.
Negative pressure therapy (NPT) has been accepted as a valuable adjunct for wound closure in adults; however, reports on its effectiveness in young children and infants, including neonates, are limited. A retrospective chart review was conducted on children treated with NPT at a single institution between January 2003 and December 2005. Wound volumetric measurements were calculated at the start and end of therapy. Sixty-eight patients with 82 wounds were identified. The mean age was 8.5 years (range 7 days-18 years). Twenty patients (29%) were 2 years of age or younger, including eight neonates. Wound types included: pressure ulcers (n=13), extremity wounds (n=18), dehisced surgical wounds (n=19), open sternal wounds (n=10), wounds with fistulas (n=3), and complex abdominal wall defects (n=6). Low suction pressures (<100 mmHg) were generally used in children younger than 4 years of age. Following NPT, 93% of wounds decreased in volume. The average wound volume decrease was 80% (p<0.01, n=56). NPT can be effectively used to manage a variety of wounds in children and neonates. No major complications were identified in our retrospective review. Prospective studies are required to better refine the use of this technology in children.
负压疗法(NPT)已被公认为是成人伤口闭合的一种有价值的辅助方法;然而,关于其在幼儿(包括新生儿)中的有效性的报道有限。对2003年1月至2005年12月期间在单一机构接受NPT治疗的儿童进行了回顾性病历审查。在治疗开始和结束时计算伤口体积测量值。确定了68例患者的82处伤口。平均年龄为8.5岁(范围7天至18岁)。20例患者(29%)年龄在2岁及以下,包括8例新生儿。伤口类型包括:压疮(n = 13)、肢体伤口(n = 18)、手术切口裂开伤口(n = 19)、胸骨开放伤口(n = 10)、伴有瘘管的伤口(n = 3)和复杂腹壁缺损(n = 6)。4岁以下儿童一般使用低吸力(<100 mmHg)。NPT治疗后,93%的伤口体积减小。伤口体积平均减小80%(p<0.01,n = 56)。NPT可有效用于处理儿童和新生儿的各种伤口。在我们的回顾性审查中未发现重大并发症。需要进行前瞻性研究以更好地完善该技术在儿童中的应用。