Frank P, Schoenhard G L, Burton E
Department of Corporate Drug Development, Searle, Skokie, Illinois 60077.
J Pharmacol Methods. 1991 Nov;26(3):233-8. doi: 10.1016/0160-5402(91)90047-9.
A technique is described for the collection of blood samples after dilation of rat tail veins using a controlled temperature device. Frequent blood samples of seven or eight per rat were collected during a 6-hr period. Further samples were taken from the same vein after recannulation during the next 5 days. This technique was also used to administer drugs intravenously through one vein and to collect blood samples from the contralateral vein.
描述了一种使用控温装置在大鼠尾静脉扩张后采集血样的技术。在6小时内，每只大鼠频繁采集7或8次血样。在接下来的5天内，重新插管后从同一条静脉采集更多血样。该技术还用于通过一条静脉静脉注射药物，并从对侧静脉采集血样。
