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生物材料对脉冲非消融性二氧化碳激光照射的温度响应

Temperature response of biological materials to pulsed non-ablative CO2 laser irradiation.

作者信息

Brugmans M J, Kemper J, Gijsbers G H, van der Meulen F W, van Gemert M J

机构信息

Laser Center, Academic Medical Center, Amsterdam, The Netherlands.

出版信息

Lasers Surg Med. 1991;11(6):587-94. doi: 10.1002/lsm.1900110614.

DOI:10.1002/lsm.1900110614
PMID:1753852
Abstract

This paper presents surface temperature responses of various tissue phantoms and in vitro and in vivo biological materials in air to non-ablative pulsed CO2 laser irradiation, measured with a thermocamera. We studied cooling off behavior of the materials after a laser pulse, to come to an understanding of heat accumulation and related thermal damage during (super) pulsed CO2 laser irradiation. The experiments show a very slow decay of temperatures in the longer time regime. This behavior is well predicted by a simple model for one-dimensional heat flow that considers the CO2 laser radiation as producing a heat flux on the material surface. The critical pulse repetition frequency for which temperature accumulation is sufficiently low is estimated at about 5 Hz. Although we have not investigated the ablative situation, our results suggest that very low pulse frequencies in microsurgical procedures may be recommended.

摘要

本文展示了各种组织体模以及体外和体内生物材料在空气中对非消融脉冲二氧化碳激光照射的表面温度响应,这些响应是用热成像仪测量的。我们研究了激光脉冲后材料的冷却行为,以了解(超)脉冲二氧化碳激光照射期间的热量积累及相关热损伤。实验表明,在较长时间范围内温度衰减非常缓慢。这种行为可以通过一个简单的一维热流模型很好地预测,该模型将二氧化碳激光辐射视为在材料表面产生热通量。估计温度积累足够低时的临界脉冲重复频率约为5赫兹。虽然我们没有研究消融情况,但我们的结果表明,在显微外科手术中可能推荐非常低的脉冲频率。

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