Khuwaja A K, Ali N S, Zafar A M
Department of Community Health Sciences, The Aga Khan University, Karachi, Pakistan.
Singapore Med J. 2007 Jun;48(6):509-13.
This study was conducted to determine the proportion of usage of psychoactive drugs, and to identify factors associated with its use among patients visiting outpatient clinics of a tertiary care hospital in Karachi, Pakistan.
A cross-sectional study was conducted involving 461 adult (age 18 years and above) patients, who were surveyed by using interviewer-administered questionnaires. All interviews were conducted by a medical students. Out of the total number of participants, 242 (52.5 percent) were males and 219 (47.5 percent) were females.
In all, 118 (25.6 percent) of the respondents were using some sort of psychoactive drugs, however, only 20 (4.3 percent) study subjects were diagnosed with any psychiatric illness. Factors found to be significantly associated with usage of psychoactive drugs included belonging to the female gender (p-value equals 0.019), older (more than 50 years) age (p-value is less than 0.001), being married (p-value equals 0.004), having formal schooling of up to 12 years (p-value equals 0.001) and physical inactivity (p-value equals 0.004). In addition, those whose family members were using psychoactive drug(s) or who suffered from non-communicable diseases were more likely to use psychoactive drugs in comparison to others (p-value is less than 0.001).
The use of psychoactive drugs is quite common in our patients regardless of having any psychiatric disease. Efforts are required to control and prevent the abuse of these drugs. Education and awareness programmes for doctors and patients may help to prevent the inappropriate use of psychoactive drugs. Regulatory intervention to control use of these drugs is also recommended.
本研究旨在确定精神活性药物的使用比例,并找出巴基斯坦卡拉奇一家三级护理医院门诊患者中与药物使用相关的因素。
开展了一项横断面研究,涉及461名成年(18岁及以上)患者,通过访谈员管理的问卷进行调查。所有访谈均由医学生进行。在参与者总数中,242名(52.5%)为男性,219名(47.5%)为女性。
总计118名(25.6%)受访者正在使用某种精神活性药物,然而,只有20名(4.3%)研究对象被诊断患有任何精神疾病。发现与精神活性药物使用显著相关的因素包括女性(p值等于0.019)、年龄较大(超过50岁)(p值小于0.001)、已婚(p值等于0.004)、接受过最高12年的正规教育(p值等于0.001)以及身体不活动(p值等于0.004)。此外,与其他人相比,家庭成员使用精神活性药物或患有非传染性疾病的人更有可能使用精神活性药物(p值小于0.001)。
无论是否患有精神疾病,精神活性药物在我们的患者中使用相当普遍。需要努力控制和预防这些药物的滥用。针对医生和患者的教育及宣传项目可能有助于防止精神活性药物的不当使用。还建议进行监管干预以控制这些药物的使用。