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与冠状动脉异常起源及并存的冠状窦有孔膜相关的猝死

Sudden death related to anomalous origin of coronary artery and coexisting fenestrated membrane of the sinus coronarius.

作者信息

Türkmen N, Eren B, Fedakar R, Durak D

机构信息

Forensic Medicine Department, Uludag University Medical Faculty, Görükle, Bursa, Turkey.

出版信息

Singapore Med J. 2007 Jun;48(6):576-8.

Abstract

Coronary artery anomalies that may be an isolated defect or part of complex congenital malformations of the heart are also often associated with a high risk of sudden death. A 19-year-old woman lost consciousness in the night. She was taken to hospital where she was treated. However, she died on the same day. The prosecutor considered the death suspicious, and the victim was taken to the morgue department for further examination and autopsy. On macroscopical examination, both coronary arteries originated from the left aortic sinus with the left one being dominant. The orifice of the sinus coronarius in the right atria was covered with a fenestrated membrane. Demonstration of coronary artery pathologies and associated anomalies in autopsies is vital for the elucidation of sudden death cases related to these lesions and for the development of new treatment approaches. The purposes of this case report are to characterise and identify markers of the coronary artery anomalies and to highlight their medicolegal importance in sudden death cases.

摘要

冠状动脉异常可能是一种孤立的缺陷,也可能是复杂先天性心脏畸形的一部分,通常也与猝死的高风险相关。一名19岁女性夜间失去意识。她被送往医院接受治疗。然而,她在同一天死亡。检察官认为这起死亡事件可疑,受害者被送往停尸房进行进一步检查和尸检。大体检查显示,两条冠状动脉均起源于左主动脉窦,以左冠状动脉为主。右心房的冠状窦口被一层有孔膜覆盖。在尸检中证实冠状动脉病变及相关异常对于阐明与这些病变相关的猝死病例以及开发新的治疗方法至关重要。本病例报告的目的是描述和识别冠状动脉异常的标志物,并强调它们在猝死病例中的法医学重要性。

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